BACKGROUND Several factors, such as compromised cardiopulmonary function, anticoagulative therapy, or anatomical deformity in the elderly, prevent general anesthesia and neuraxial blockade from being conducted for total knee replacement arthroplasty (TKRA). We investigated the efficacy of femoral/sciatic nerve block with lateral femoral cutaneous nerve block (FSNB) as an alternative procedure i...

Background: Seeking for efficient adjuvants to the regional nerve block is still under research, with medication that increases time of analgesia but lesser side effects. Objectives: The purpose this research was study safety and efficacy different additives, namely dexmedetomidine ketamine when added bupivacaine in ultrasound-guided supraclavicular block, assess onset duration sensory motor se...

BACKGROUND Postoperative pain is often severe after hallux valgus repair. Sciatic nerve blocks with long-acting local anesthetics have been recommended for surgical anesthesia and postoperative analgesia. However, a novel percutaneous approach may require less analgesia and make the procedure suitable for ambulatory care. We thus tested the hypothesis that mid-foot block and sciatic nerve block...

Background & objective: The serratus anterior plane block (SAPB) is a recent technique providing effective perioperative analgesia in thoracic surgeries. This study compared the intra–operative hemodynamics and analgesic efficacy of superficial SAPB, to deep epidural thoracotomies.
 Methodology: one hundred eighty lung cancer patients scheduled for thoracotomy were randomly allocated t...

Abstract Background This study aimed to compare the duration of postoperative analgesia using intraperitoneal bupivacaine plus neostigmine or alone. In this randomized controlled trial, we included 56 adult patients scheduled for elective laparoscopic cholecystectomy operation. Patients were randomly allocated into two groups group (B group) who received 50 ml 0.25% alone and bupivacaine-neosti...

BACKGROUND The purpose of our study is to compare two methods of postoperative analgesia in colorectal cancer patients after resectional operations, and to evaluate advantages and limitations of each method on the postoperative course of these patients. METHODS One hundred patients scheduled to undergo elective colorectal cancer surgery were randomized into two groups; after general anesthesi...

BACKGROUND Effective analgesia is essential for the postoperative care of orthopedic patients. OBJECTIVES To evaluate the efficacy of continuous fascia iliaca compartment block (FIB) as postoperative analgesia after hip fracture surgery, and to compare FIB with patient-controlled intravenous analgesia (PCIA) using fentanyl for 48 h postoperatively. METHODS Patients with hip fractures who we...

BACKGROUND Different additives have been used to prolong regional blockade. We designed a prospective, randomized, double-blind, controlled clinical trial to evaluate the effect of dexamethasone added to bupivacaine-fentanyl on the duration of postoperative analgesia via epidural catheterization. METHODS Seventy two adult patients scheduled for elective abdominal or thoracic surgery under epi...

Background: The aim of the study was to assess the efficacy of ropivacaine with clonidine as an adjuvant given via single shot caudal epidural in pediatric patients for intraoperative and postoperative pain relief. Materials and Methods: In this study, 30 children of ASA-I-II, aged 1-6 years scheduled for infra-umbilical surgical procedures were given ropivacaine 0.125% 1 ml/kg + clonidine 1μg/...