Well-defined doubly pH-responsive schizophrenic diblock copolymer nanoparticles with tunable isoelectric points are prepared via RAFT aqueous dispersion polymerization using an efficient one-pot protocol.

Objective: The aim of present research was to compare the quality of life in caregivers of acute and chronic schizophrenic patients. Methods: Considering the inclusion and exclusion criteria, 30 participants were selected through purposive sampling method among the caregivers of acute and chronic schizophrenic patients. The sample answered to WHO Quality Of Life (WHOQOL-100) and demographic ...

This article focuses on the schizophrenic disorganization syndrome, which was initially described by Bleuler (who used the term "dissociation") as lying at the heart of schizophrenia. While adopting a neo-Bleulerian approach, we describe schizophrenic disorganization using a pathogenetic hypothesis and a three-part structure. First, we discuss previous approaches to characterizing and defining ...

The present study measured prefrontal cortical gray and white matter volume in chronic, male schizophrenic subjects who were characterized by a higher proportion of mixed or negative symptoms than previous patients that we have evaluated. Seventeen chronic male schizophrenic subjects and 17 male control subjects were matched on age and handedness. Regions of interest (ROI) were measured using h...

In a study of sixty institutionalist Schizophrenic patients, sixty chronic schizophrenic outpatients and an equal number of age and sex matched normal controls from the same regional background, the prevalence of HBsAG was six, one and zero respectively. Institutionalized schizophrenic patients are a high risk group for hepatitis B virus infection.

A case which initially presented with schizophrenic symptoms and was being managed as a patient of schizophrenic illness with tardive dyskinesia for 12 years, was on careful review of history and examination diagnosed as having Huntington's Disease. Clinical and theoretical aspects of Huntington's disease presenting with schizophrenic symptoms, and neurological deficits which are seen in schizo...

OBJECTIVE Ever since the characterization of schizophrenia, clinicians have noted abnormal pain sensitivity in their patients. The published literature, however, is inconsistent concerning the nature of the change reported. The objective of this study was to characterize the pain response profile of schizophrenic patients by providing both acute and prolonged (i.e., rapidly repeating) painful s...