OBJECTIVE Investigating the factor structure of schizotypal traits in normal population is important to describe the clinical phenotypes associated with susceptibility to schizophrenia. Schizotypal Personality Questionnaire (SPQ) is a commonly used self-rated measure to assess schizotypal traits. While Raine's three-factorial model is most commonly supported model explaining factor structure of...

The brain derived neurotrophic factor (BDNF) val66met polymorphism rs6265 influences learning and may represent a risk factor for schizophrenia. Healthy people with high schizotypal personality traits display cognitive deficits that are similar to but not as severe as those observed in schizophrenia and they can be studied without confounds of antipsychotics or chronic illness. How genetic vari...

Schizotypal traits are of interest and importance in their own right and also have theoretical and clinical associations with schizophrenia. These traits comprise attenuated psychotic symptoms, social withdrawal, reduced cognitive capacity, and affective dysregulation. The link between schizotypal traits and psychotic disorders has long since been debated. The status of knowledge at this point ...

BACKGROUND The schizotypal personality disorder is a recent psychiatric nosological concept developed by Spitzer at the end of the 1970s, based on the analysis of the characteristics of relatives of schizophrenic subjects included in the adoption studies carried out in the same decade by Kety, Wender and Rosenthal. HISTORICAL ASPECTS However, this entity is based on older observations, at the...

Studies that have investigated whether deficits in social cognition observed in schizophrenia are also present in schizotypal individuals have largely been inconclusive, and none of these studies have examined social interactive behavior. Here, we investigated interactive decision-making behavior in individuals differing in the amount of schizotypal symptoms using tasks derived from Game Theory...

Larrison, Abigail L., Carolyn F. Ferrante, Kevin A. Briand, Anne B. Sereno: Schizotypal Traits, Attention and Eye Movements. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 2000,24, pp. 357-372. 02000 Elscvicr S&n= Inc. 1. Subjects demonstrating high, average, or low schizotypal traits participated in saccade tasks of eye movements and attention including: a simple saccade task, an antisaccade t...

The current study aimed to determine whether there is a specific neurocognitive deficit in individuals with schizotypal personality features. One hundred and fifty-nine healthy participants and 62 schizotypal individuals completed a comprehensive battery of cognitive tests. The cognitive functions captured by the battery could be reduced to 6 factors. Significant difference was found between pa...

While two factors are currently thought to underlie individual differences in schizotypal personality, three factors may best explain schizotypal traits. This study used confirmatory factor analysis to assess five competing models of schizotypal personality in the general population: null model, one-factor model, simple two-factor model, Kendler two-factor model, and three-factor model. The com...