We describe a case of young adult female with Henoch-Schonlein purpura (HSP) presenting cutaneous and gastrointestinal manifestations. Biopsy revealed leukocytoclastic vasculitis in the skin. Steroid therapy led to initial resolution symptoms followed by relapse rashes subsequent introduction azathioprine. HSP is most common childhood uncommonly seen adults. Early recognition disease, especiall...

INTRODUCTION Renal involvement is the major cause of mortality and morbidity in children with Henoch-Schonlein purpura. The purpose of this study was to determine the predictive factors of Henoch-Schonlein nephritis (HSN) and correlations between clinical and pathologic findings. MATERIALS AND METHODS Demographic characteristics and clinical manifestations of 105 children with Henoch-Schonlei...

Henoch-Schonlein Purpura (HSP) is an acute immunoglobulin A (IgA)–mediated disorder characterized by generalized vasculitis. HSP commonly occurs in children. The annual worldwide incidence 13-20 per 100,000 children under 17 years of age.1–3 It non-thrombocytopenic palpable purpura mostly located on the dependent parts like lower extremities and buttocks, arthralgia/arthritis, bowel angina, hem...

bacterial and viral triggers are suspected agents in the initial etiology of autoimmune diseases. there are some studies on the etiology of autoimmune disorders which have focused on streptococcal infection and a possible relation with microbial heat shock proteins (hsp) which show significant homology with human heat shock proteins. in addition, some serotypes of streptococci cross-react with ...

Purpose: In order to understand the prognosis and provide reasonable diagnosis for Henoch-Schonlein purpura nephritis (HSPN) in children, we collected the clinical, pathological data and analyzed the relationship between the variables and outcomes to elicit the importance of pathologicalgrading in HSPN treatment. Methods: Analyses of 159 cases of clinical and pathological data of HSPN in childr...

the aim of this study was to investigate the possible influence of interferon-gamma (ifn- γ) gene polymorphism +874 (a/t) (rs2430561) in the susceptibility and renal complications of patients with henoch-schonlein purpura (hsp). we also studied the effects of ifn-γ allelic variation on serum levels of pro-and anti-inflammatory cytokines in hsp patients. the  study  population  comprised  97  pa...

An eight year old boy with Henoch-Schonlein Purpura (HSP) presented with acute compartment syndrome (ACS) of his left hand following arterial cannulation of his radial artery in intensive care unit. Emergency decompression and fasciotomy were performed. The authors report this first case in literature and discuss how HSP can be complicated by ACS and ways to prevent the latter from happening.

Henoch-Schonlein purpura (HSP) is primarily a childhood immunoglobulin A (IgA)-mediated illness. When adults are affected, malignancy can be associated. We present a rare case of HSP in a 75-year-old man with malignant pleural mesothelioma. He presented with episodes of dizziness and subsequently developed non-palpable purpura across his legs, arthralgia, hematuria, proteinuria, and acute renal...