Atopic dermatitis (AD), the most common chronic inflammatory Background skin disease, is evolving as a systemic disease, and associated systemic inflammation is possibly linked to increases in cardiovascular disease. : We assessed levels of the inflammatory marker CRP in 59 patients Methods with moderate-to-severe AD compared to matched healthy controls, and to determine correlation with skin d...

quality of life of pediatric patients in the age group of 5–16 years, and their parents, assisted at the Dermatology Department of Universidade do Estado do Pará in 2015. Methods: A cross-sectional study including 51 patients and their guardians, to whom two questionnaires about the quality of life were applied, the Children’s Dermatology Life Quality Index (CDLQI) and the Dermatitis Family Imp...

In this study the routine use of different parameters for evaluation of the overall therapeutic outcome in atopic dermatitis was investigated. The disease activity of 117 randomly selected hospitalized patients suffering from atopic dermatitis was routinely assessed using the Severity Scoring of Atopic Dermatitis (SCORAD) index on admission and at discharge. Serum levels of eosinophil cationic ...

BACKGROUND Atopic dermatitis (AD) is a chronic allergic inflammatory disease, which manifests itself with eczematous skin lesions. OBJECTIVE We compared the clinical efficacy of tacrolimus ointment (0.1%) given twice a day and oral cyclosporine (3 mg/kg) given once daily. Rescue medication for itching included cetirizine 10-20 mg (equal to one or two tables). METHODS Thirty patients, aged 1...

background studies revealed that severity of atopic dermatitis correlates with colonization by s.aureus and the density of bacteria and antibiotic resistance is one of the factors in s.aureus recolonization. objectives we aimed to determine the pattern of colonization with different subtypes of s.aureus in patients with atopic dermatitis and its correlation with scorad (scoring atopic dermatiti...

Introducción: La dermatitis atópica es una enfermedad crónica de la piel que se caracteriza por parches eritematosos y pruriginosos afecta hasta a un 20% población pediátrica. Actualmente, desconoce causa exacta el manejo incierto sin embargo, uso suplementos vitamínicos puede estar relacionado estado preventivo mejora calidad vida del paciente. Objetivo: Correlacionar los niveles vitamina D en...

Background: Eczema or atopic dermatitis (AD) is one of the most prevalent skin diseases in the world. Although, the disorder is not fatal, it can cause life quality reduction. The aim of the current study was to investigate the impact of atopic dermatitis on life quality of 1-6-year-old children. Materials and Methods: The current study is a descriptive and analytical one designed to assess qu...

BACKGROUND/OBJECTIVES Atopic dermatitis (AD), a chronic inflammatory skin disease, is accompanied by disruption of the epidermal lipid barrier, of which ceramide (Cer) is the major component. Recently it was reported that vitamin C is essential for de novo synthesis of Cer in the epidermis and that the level of vitamin C in plasma is decreased in AD. The objective of this study was to determine...

BACKGROUND Eczema is one of the most common chronic inflammatory skin diseases, affecting about 20% of children. The pathogenic mechanisms of eczema are still not fully understood, and current treatment of moderate-severe eczema is often difficult. Recently, it has been suggested that Vitamin D plays a key role in this disease, even if mechanisms are only partially known. OBJECTIVE The purpos...

The value of CD30 and the soluble circulating fragment of CD30 (sCD30) for atopic dermatitis (AD) remains unclear. In particular, little is known about the effects of age, duration of disease and Scoring Atopic Dermatitis index (SCORAD) on the levels of serum sCD30 in patients affected by AD. In the present study, we have analysed serum sCD30 levels of adult patients affected by AD. The study's...