It has long been believed that colorectal cancer evolves from a precursor lesion, the adenomatous polyp. This concept was based on the elegant pathology studies from the St Mark’s Hospital, London, published by LockhartMummery and Dukes in 1928, and culminating in the concept of the polyp-cancer sequence published in 1975 by Muto and colleagues. The introduction of colonoscopy in the early 1970...

It has long been believed that colorectal cancer evolves from a precursor lesion, the adenomatous polyp. This concept was based on the elegant pathology studies from the St Mark’s Hospital, London, published by LockhartMummery and Dukes in 1928, and culminating in the concept of the polyp-cancer sequence published in 1975 by Muto and colleagues. The introduction of colonoscopy in the early 1970...

BACKGROUND While several tests and strategies are recommended for colorectal cancer (CRC) screening, studies suggest that primary care providers often recommend colonoscopy without providing information about its risks or alternatives. These observations raise concerns about the quality of informed consent for screening colonoscopy. METHODS We conducted a telephone survey (August 2008 to Sept...

Life expectancy in Korea has increased, and the number of screening colonoscopies in the elderly has also dramatically increased. The net benefit of colonoscopy in the very elderly (≥80 years of age as defined by the World Health Organization) may be reduced because of the competing risk of mortality due to other diseases. Therefore, the decision to perform screening colonoscopy may be more com...

OBJECTIVE To determine FPs' choices of and opinions on colorectal cancer (CRC) screening options in the context of a new provincewide screening program. METHODS Mailed survey, using a modified Dillman protocol, which asked about 5 recommended CRC screening modalities. SETTING Ontario. PARTICIPANTS Computer-generated random sample of 894 eligible FPs and GPs from a commercially available p...

BACKGROUND Fecal occult blood testing, flexible sigmoidoscopy, and colonoscopy are used to screen patients for colorectal cancer. OBJECTIVE To compare the cost-effectiveness of fecal occult blood testing, flexible sigmoidoscopy, and colonoscopy. DESIGN The cost-effectiveness of the three screening strategies was compared by using computer models of a Markov process. In the model, a hypothet...

IMPORTANCE—Colorectal cancer (CRC) screening saves lives, but participation rates are low among underserved populations. Knowledge on effective approaches for screening the underserved, including best test type to offer, is limited. OBJECTIVE—To determine (1) if organized mailed outreach boosts CRC screening compared with usual care and (2) if FIT is superior to colonoscopy outreach for CRC scr...

BACKGROUND Screening colonoscopy effectiveness is hampered by limited adherence by the general population. The present prospective study was performed to evaluate whether adding capsule colonoscopy to the endoscopic screening options increases uptake. METHODS Invitation letters were sent to 2150 persons above the age of 55 insured with a German medical insurance company in the area of Rinteln...

This document updates the colorectal cancer (CRC) when persons up to date with screening, who have prior screening recommendations of the U.S. Multi-Society Task Force of Colorectal Cancer (MSTF), which represents the American College of Gastroenterology, the American Gastroenterological Association, and The American Society for Gastrointestinal Endoscopy. CRC screening tests are ranked in 3 ti...

Measures shown to improve the adenoma detection during colonoscopy (excellent bowel preparation, cecal intubation, cap fitted colonoscope to examine behind folds, patient position change to optimize colon distention, trained endoscopy team focusing on detection of subtle flat lesions, and incorporation of optimum endoscopic examination with adequate withdrawal time) are applicable to clinical p...