Background. Toxocariasis is an important zoonotic infection, especially in tropical areas. One of the significant challenges serodiagnosis human toxocariasis cross-reaction Toxocara antigens with other parasites due to their relatively similar glycan structures. Removing structure from excretory-secretory (TES) may increase efficacy these diagnosis toxocariasis. The current study aimed assess d...

strongyloidiasis, caused by a nematode parasite so-called strongyloides stercoralis is one of the major human intestinal nematode infections. considering that stool examination for strongyloides larvae is not a sensitive method and immunodiagnostic methods are more applicable for this purpose, so the present study was conducted to compare the somatic (s) and excretory - secretory (es) antigens ...

The humoral response to the gastrointestinal (GI) flora was analyzed in secretory Ig (sIg)-deficient polymeric IgR (pIgR)(-/-) mice and otherwise congenic C57BL/6 mice. While both strains carried an ileal flora of similar size and composition, increased bacterial translocation to mesenteric lymph node was demonstrated in pIgR(-/-) mice. Serum IgA was greatly increased in pIgR(-/-) mice compared...

human fascioliasis due to unknown species and animal fascioliasis caused by both or one of fasciola spp. are commonly seen in iran. to compare electrophoretic patterns of somatic and excretory-secretory antigens of f. hepatica and f. gigantica  by sodium dodecyl sulphate polyacrylamide gel electrophoresis (sds-page), the adult flukes were collected from infected slaughtered bovine livers. e/s a...

Monoclonal antibodies to insulin secretory granule membranes were obtained following immunization of mice with granule membranes purified from a rat transplantable insulinoma. The specificities of the antibodies were investigated by using binding assays with different insulinoma subcellular fractions, by indirect immunofluorescence studies with intact and permeabilized cells, and by immunoblott...

The efferent limb of secretory immunity depends on local production and selective epithelial transport of polymeric immunoglobulins (pIg). To this end there is a fascinating cooperation of the B-cell system and the epithelium with their production of two key factors, the J chain and the secretory component (SC), respectively. Interactions between activated leucocytes for example, T cells and ma...