INTRODUCTION TO PLANT PATHOLOGY. New second edition By FREERICK DEFOREST HFEALD, Professor Emeritus of Plant Pathology, The State College of Washington. McGraw-Hill Publications in the Agricultural Sciences. 603 pages, 6 x 9, 246 illustrations, $4.00 In revising this well-known text, the author has retained his general plan of presenting a rounded, detailed introduction, in which the significan...

A mouse model of amyotrophic lateral sclerosis-parkinsonism-dementia complex based on the consumption of cycad seed flour was used to determine whether the observed pathology of motor neuron loss begins in the distal axons or the spinal cord. Assessments of neuromuscular junction integrity and motor neurons were performed at multiple time points. Mice fed cycad pellets performed worse on the wi...

Neurofibrillary tau pathology (tangles and threads) and extracellular amyloid-β (Aβ) pathology are defining features of Alzheimer's disease. For 25 years, most research has focused on the amyloid hypothesis of AD pathogenesis and progression. But, because of failures in clinical trials of Aβ-targeted therapies and the new concept of prion-like propagation of intracellular abnormal proteins, tau...

OBJECTIVE Pumpkin seed oil is rich in phytoestrogens and animal studies suggest that there is some benefit to supplementation in low estrogen conditions. This study is the first to evaluate the benefit of pumpkin seed oil in postmenopausal women. METHODS This pilot study was randomized, double-blinded and placebo-controlled. Study participants included 35 women who had undergone natural menop...

Recent evidence suggests that tau aggregates are not only neurotoxic, but also propagate in neurons acting as a seed for native tau aggregation. Prion-like tau transmission is now considered as an important pathogenic mechanism driving the progression of tau pathology in the brain. However, prion-like tau species have not been clearly characterized. To identify infectious tau conformers, here w...

Growing evidence suggests that diabetes mellitus (DM) is one of the strongest risk factors for developing Alzheimer's disease (AD). However, it remains unclear why DM accelerates AD pathology. In cynomolgus monkeys older than 25 years, senile plaques (SPs) are spontaneously and consistently observed in their brains, and neurofibrillary tangles are present at 32 years of age and older. In labora...

Subfamily-specific Fluorescent Probes for Cys proteases Display Dynamic 1 Protease Activities During Seed Germination 2 3 Haibin Lu, Balakumaran Chandrasekar, Julian Oeljeklaus, Johana Misas-Villamil, 4 Zheming Wang, Takayuki Shindo, Matthew Bogyo, Markus Kaiser, Renier A. L. van der 5 Hoorn 6 7 1 The Plant Chemetics Laboratory, Department of Plant Sciences, University of Oxford, OX1 8 3RB Oxfo...

AIMS To develop a highly sensitive and rapid protocol for simultaneous detection and differentiation of Tobacco mosaic virus (TMV) and Tomato mosaic virus (ToMV) in pepper and tomato. In this study, we use the multiplex PCR technique to detect dual infection of these two viruses. METHODS AND RESULTS A multiplex RT-PCR method consisting of one-tube reaction with two primer pairs targeted to re...

A laboratory experiment was carried out at the Professor GAF Seed Pathology Centre and Laboratory of Department Science Technology, Bangladesh Agricultural University (BAU), Mymensingh during period July 2018 to January 2019 determine effect seed sources on quality health status in some Transplanted Aman rice varieties Bangladesh. Among sources, moisture content recorded from 10.40% 13.37%. In ...

The experiment on “Effect of fungicides Sclerotium rolfsii isolates groundnut from Khandesh region” was conducted at Plant Pathology Section, College Agriculture, Dhule. results obtained are presented here under. Groundnut (Arachis hypogea L.) is a major edible oil seed crop tropical and subtropical region the world. It world’s fourth important source third vegetable protein also seeds, vines d...