There is an urgent need to develop data integration and testing strategy frameworks allowing interpretation of results from animal alternative test batteries. To this end, we developed a Bayesian Network Integrated Testing Strategy (BN ITS) with the goal to estimate skin sensitization hazard as a test case of previously developed concepts (Jaworska et al., 2010). The BN ITS combines in silico, ...

We analyze an alternative to the standard rationalizability requirement for observed choices by considering non-deteriorating selections. A selection function is a generalization of a choice function where selected alternatives may depend on a reference (or status quo) alternative in addition to the set of feasible options. A selection function is non-deteriorating if there exists an ordering o...

A central concern of systems engineering is selecting the most preferred alternatives for implementation from among competing options. The selection process is sometimes called tradeoff analysis, and is often built on the methods of decision analysis and utility theory. The process can be loosely divided into two parts, a first part in which one determines the relative priority of various requi...

Context and Motivation: The notion of goal and goal models is ideal for the alternative systems. Goal models provide us different alternatives during goal oriented requirements engineering. Question/Problem: Once we find different alternatives, we need to evaluate these alternatives to select the best one. Ideas: The selection process consists of two main parts. In first part of the selection p...