BACKGROUND After completion of axillary dissection, many breast cancer patients with axillary sentinel nodal involvement are found to have regional disease limited to the sentinel nodes. These patients are exposed to the morbidity of axillary clearance without any expected therapeutic benefit. METHODS Sentinel node biopsy was performed either with Patent blue dye or with a combined dye, radio...

IMPORTANCE A practice gap exists in the surgical removal of sentinel lymph nodes, from removal of only the most radioactive (hottest) lymph node to removal of all lymph nodes with radioactivity greater than 10% of the hottest lymph node. OBJECTIVE To determine the clinical significance of melanoma in sentinel lymph nodes that are not the hottest sentinel node and to determine the risk for dis...

lymph node status remains an important prognostic indicator for survival in breast cancer. sentinel lymph node biopsy has become the standard method of assessment of clinically node negative breast cancers. economic implications as well as patient related factors have lead to the development a number of intra-operative techniques. review of the emerging trends in the last 4 years show that alth...

Introduction Sentinel lymph node biopsy is indicated for patients with biopsy-proven thickness melanoma greater than 1.0 mm. Use of lymphoscintigraphy along with vital blue dyes is the gold standard for identifying sentinel lymph nodes intraoperatively. Indocyanine green (ICG) has recently been used as a method of identifying sentinel lymph nodes. We herein describe a case series of patients wh...

BACKGROUND The objectives of the study were to determine how often a sentinel lymph node is visualized by lymphoscintigraphy in breast carcinoma patients, how often the sentinel lymph node is identified during surgery, and the sensitivity of these procedures to identify the presence of axillary lymph node metastasis. METHODS A total of 136 patients were enrolled in 2 hospitals. Preoperative d...

background: sentinel node biopsy (slnb) is the standard of care for breast cancer treatment and it is getting wide acceptance in iran. the radiation safety of the procedure has been investigated under controlled conditions, but the standard dose of radiotracer and techniques are not always observed in the community setting. the aim of this study was to assess the magnitude of the absorbed doses...

BACKGROUND We investigated the presence and distribution of the sentinel and the non-sentinel node micrometastases using complete serial sectioning and immunohistochemical staining (IHC), to inspect whether lymph node micrometastases spread to the sentinel lymph nodes first. METHODS A total of 35 patients, who underwent gastrectomy with a sentinel lymph node biopsy for gastric cancer, were en...

BACKGROUND In patients with clinically node-negative breast cancer, diagnosed with palpation and several types of imaging examination, sentinel lymph nodes accurately predict the status of the other axillary nodes, which determine the nature of subsequent adjuvant treatment. In addition, compared with axillary lymph node dissection, sentinel-node biopsy results in less postoperative morbidity, ...

OBJECTIVE To establish the prognostic value of knowledge of sentinel node status in melanoma. DESIGN Single centre prospective observational study, with sentinel nodes identified by lymphoscintigraphy, gamma probe, and intraoperative blue dye and examined by both conventional histopathology and immunopathology. SETTING Specialist surgical service in west of Scotland. PARTICIPANTS 482 pati...

UNLABELLED Laparoscopic evaluation of sentinel nodes is useful for staging prostate cancer, but preoperative localization of deep abdominal sentinel nodes with planar lymphoscintigraphy is difficult. We evaluated the value of SPECT/CT for detecting and localizing sentinel nodes in prostate cancer. METHODS (99m)Tc-nanocolloid was injected peri- and intratumorally, guided by transrectal ultraso...