background management of bacterial sepsis as a common cause of hospitalization and a life threatening clinical syndrome is a challenge. in previous studies, incorrect diagnosis of sepsis and unnecessary treatment have been frequently reported. objectives the aim of this study was to evaluate the diagnosis and treatment of cases with a primary diagnosis of sepsis. patients and methods of 410 med...

Sepsis, manifested by systemic inflammatory response syndrome (SIRS), septic shock and multiple organ dysfunction syndrome (MODS), remains the leading cause of morbidity and mortality in critically ill patients. Despite advances and our knowledge of sepsis, there remain clinical dilemmas that impact how we treat patients. These clinical dilemmas include hypotension, cardiac dysfunction and alte...

Plasma carbon monoxide (CO) concentrations were measured in 12 patients with sepsis syndrome. CO concentrations were found to be significantly increased in patients compared with those in 30 normal controls. Patients with septic shock had significantly higher plasma CO concentrations than those without shock. Results suggest that CO might play an important role in paediatric sepsis syndrome.

This article reviews the current understanding of sepsis, severe sepsis, and septic shock. The article details definitions and epidemiology pertinent to the sepsis syndrome. A brief discussion of mechanisms of disease is followed a description of organ-specific failures related to sepsis. A concise review of the latest treatment options for each organ dysfunction is provided.

Sepsis is defined as the combination of pathologic infection and physiological changes known collectively as the systemic inflammatory response syndrome (Martin, 2003). This response results in physiological alterations that occur at the capillary endothelial level. In the early stages, the clinical manifestations of this process are unspecific and it is often underappreciated in clinical pract...

INTRODUCTION Acute compartment syndrome is a surgical emergency requiring immediate fasciotomy. Spontaneous onset of acute compartment syndrome of the lower limbs is rare. We present a very rare case of pneumococcal sepsis leading to spontaneous acute compartment syndrome. CASE PRESENTATION A 40-year-old Caucasian man presented as an emergency with spontaneous onset of pain in both legs and s...

Edward’s syndrome is commonly known as the trisomy 18 syndrome. It a devastating genetic disorder that can be characterized by multiple congenital anomalies. About 50% babies with this do not survive beyond one week of age and approximately 95% does past first year life. The feature Syndrome involves in craniofacial, skeletal, cardiovascular, central nervous system genitourinary malformations. ...

Introduction: Beat-to-beat variation in heart rate shows a complex dynamics, and this complexity is changed during systemic inflammatory response syndrome (e.g. sepsis). It is not known whether or not cardiac pacemaker dynamical rhythm is affected by sepsis. The aim of this study was to investigate heart rate dynamics of isolated heart as well as expression of pacemaker channels (HCN) in a r...

Diabetes and sepsis are major contributors of morbidity mortality around the world, with diabetic patients accounting for majority post-sepsis comorbidities escalating rates. is undoubtedly a key comorbid syndrome due to its high frequency propensity affect critical parts pathogenesis; however, precise impact diabetes on infection progression elusive. In individuals sepsis, dysfunctional immuno...

Background: Septic acute kidney injury (AKI), identified when sepsis and AKI present concurrently, is a syndrome of function impairment organ damage, which accounts for ~50% in the intensive care unit (ICU).