Five control and ten estrogen treated albino rats were studied for changes in sodium and potassium in serum, heart, muscle, uterus and brain. The serum levels of sodium depleted significantly in the estrogen treated rats. Of the tissues studied, only uterus and brain had significantly sodium retention effect. The potassium levels on the other hand decreased significantly, both in serum and tiss...

The aim of this study was to investigate the correlation between the severity of coronary artery lesions in patients with acute coronary syndromes (ACS) and levels of estrogen, high-sensitivity C-reactive protein (hs-CRP) and matrix metalloproteinase-9 (MMP-9). A total of 65 patients with ACS, 33 patients with stable angina pectoris (SAP) and 36 healthy controls were randomly enrolled. Patients...

INTRODUCTION Acute kidney injury is a serious,sexually dimorphic perioperative complication, primarily attributed to hypoperfusion. We previously found that estradiol is renoprotective after cardiac arrest and cardiopulmonary resuscitation in ovariectomized female mice. Additionally, we found that neither estrogen receptor alpha nor beta mediated this effect. We hypothesized that the G protein ...

INTRODUCTION There is a sex difference in the risk of ischemic acute kidney injury (AKI), and estrogen mediates the protective effect of female sex. We previously demonstrated that preprocedural chronic restoration of physiologic estrogen to ovariectomized female mice ameliorated AKI after cardiac arrest and cardiopulmonary resuscitation (CA/CPR). In the present study, we hypothesized that male...

objectives: the purpose of this study was to consider the effect of eight weeks aerobic training on pth, albumin, calcium, alkaline phosphatesand estrogen levels in postmenopausal women. methods & materials: 22 postmenopause women, 55-70 years, of jahandidegan center in tehran were selected and randomly divided into two groups: (experimental (12) and control (10)) .they had aerobic training pro...

the purpose of this research was the study of reproductive performance in postpartum dairy cows with different parities. twenty holstein dairy cows were assigned into two equal primiparous and multiparous groups. body weight and body condition score (based on 1-5 scoring) were measured every other week, starting from two weeks before calving till pregnancy confirmation. daily milk yield was als...

Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of vascular disease. Clinical studies have shown that postmenopausal women have higher serum TNF-alpha levels; however, whether this increase in TNF-alpha is associated with vascular dysfunction is unknown. We investigated whether estrogen deficiency is associated with increased serum TNF-alpha levels and tested the effects...

Apolipoprotein M (apoM) is present predominantly in high-density lipoprotein (HDL) in human plasma, thus possibly involved in the regulation of HDL metabolism and the process of atherosclerosis. Although estrogen replacement therapy increases serum levels of apoAI and HDL, it does not seem to reduce the cardiovascular risk in postmenopausal women. Therefore, we investigated the effects of estro...

Role of the bed nucleus of stria terminalis (BST) in the control of gonadotropin release in the female rat was studied. Electrical stimulation of the BST on the day of diestrus II increased the serum concentration of FSH, but not of LH. The stimulation on the day of estrus increased serum concentration of LH as well as on the day of proestrus. In the ovariectomized and estrogen-treated rat, the...

Xenoestrogens, such as o,p'-DDT and octyl phenol (OP), have been associated with reproductive abnormalities in various wildlife species. Xenoestrogens mimic the natural estrogen 17 beta-estradiol and compete for binding to the estrogen receptor. Even though the affinity of o,p'-DDT and OP for the estrogen receptor is approximately 1000-fold lower than 17 beta-estradiol, the actions of xenoestro...