Analysis of serum free fatty acids by gas-liquid chromatography showed high proportions (27-57%) of octanoic acid for up to 4 hr after the ingestion of a single oral load of medium-chain triglyceride (approximately 1 g/kg body weight) in four volunteers. The effects of a medium-chain triglyceride load on the concentrations of plasma free long-chain fatty acids, plasma glucose, serum insulin, an...

Acyl CoA/diacylglycerol acyltransferase (DGAT) 1 is one of two known DGAT enzymes that catalyze the final and only committed step in triglyceride biosynthesis. The purpose of this study was to test the hypothesis that chronic inhibition of DGAT-1 with a small-molecule inhibitor will reduce serum triglyceride concentrations in both genetic and diet-induced models of hypertriglyceridemia. Zucker ...

Streptozotocin (STZ)-induced diabetic mice increased levels of serum glucose, triglyceride and cholesterol, and decreased level of serum insulin. Effects of Bofutsushosan (BOF: Pulvis ledebouriellae compositae: 防風通聖 散) and its composed crude drug, gardeniae fructus (GF: 山梔子) were investigated on levels of these diabetic parameters (serum glucose, insulin, triglyceride and cholesterol) in STZ-di...

The methodology to distinguish the patients showing considerable fluctuation of the whole blood concentration of cyclosporin A (CYA) was investigated from a viewpoint of laboratory test values. First, we retrospectively examined the CYA trough blood concentrations monitored continuously. The patients were classified into three groups by the fluctuation of CYA trough blood concentrations during ...

As genetically determined apolipoprotein E (apo E) phenotypes influence serum cholesterol concentration, we analysed whether serum triglyceride values are also affected by the apo E phenotypes in infants. Non-fasting serum triglyceride values were measured in 7- and 13-month-old participants in the STRIP project, a randomised, prospective trial aimed at reducing children's exposure to known ath...

The influence of the aqueous crude extract of Glycine tomentella root (Leguminosae) on lipid metabolism was investigated in hyperlipidemic hamsters. It was found that the administration of the G. tomentella extract (GTE) leads to a decrease of high serum cholesterol and triglyceride levels induced by high-fat diet. The GTE also increased serum high-density lipoprotein (HDL) cholesterol and decr...

Introduction: Hyperlipidemia is one of the most important and common risk factors of cardiovascular diseases especially Atherosclerosis and consequently CHD. Unalike age and gender, hyperlipidemia is a factor which can be controlled by altering the life style, nutritional habits and medical-medicinal interventions. Although serum level of cholesterol is always noticed in hyperlipidemia, hypertr...

Introduction: Hyperlipidemia is one of the most important and common risk factors of cardiovascular diseases especially Atherosclerosis and consequently CHD. Unalike age and gender, hyperlipidemia is a factor which can be controlled by altering the life style, nutritional habits and medical-medicinal interventions. Although serum level of cholesterol is always noticed in hyperlipidemia, hypertr...

recent studies have documented the importance of lipids and lipoproteins as determinants of serum total homocysteine concentrations in persons with myocardial infarction, and in healthy subjects. associations between various biological systems and total homocysteine have also been reported. however, some of these associations are poorly understood. the purpose of our study was to measure serum ...

purpose: to evaluate the effects of silver nanoparticles on some serum parameters in mice. materials and methods: forty mice, including twenty male and twenty female, were randomly divided into eight groups: c1 and c2 (male and female control groups, respectively), t1, t2 and t3 (male treatment groups), t4, t5 and t6 (female treatment groups). after the acclimatization period, the treatment gro...