an experimental study has been made of the hydrodynamics of a stage mixer-settler to obtain appropriate design information. in this paper several tests were done according to full factorial design of experiments with high reliability, since each test recurs seven times and the results of  them are very close to each other(p=1bar and t=25 °c). sauter diameter in each test is determined with phot...

Using a nuclease-dead Cas9 mutant, we show that Cas9 reproducibly induces chromatin accessibility at previously inaccessible genomic loci. Cas9 chromatin opening is sufficient to enable adjacent binding and transcriptional activation by the settler transcription factor retinoic acid receptor at previously unbound motifs. Thus, we demonstrate a new use for Cas9 in increasing surrounding chromati...

However ATPE has no large-scale industrial applications yet. This is based substantially on very long phase separation times resulting from low interfacial tensions and low density differences between the phases producing intensive and stable emulsions. This causes an increased footprint of the required mixer/settler devices or the application of additional equipment such as energy consuming ce...

Continuous counter-current extraction of rhenium from roasting dust leach liquor was carried out using a mixer-settler extractor. Tributylphosphate was used as the extractant diluted in kerosene. The effects of the flow rates and extraction stages number were investigated. The extraction efficiency was affected by the flow rates of the aqueous and organic phases, and its mechanism was qualitati...