نتایج جستجو برای: short tandem repeat strs
تعداد نتایج: 527873 فیلتر نتایج به سال:
AIM To characterize the noise and stutter distribution of 23 short tandem repeats (STRs) included in the PowerSeqTM Auto System. METHODS Raw FASTQ files were analyzed using STRait Razor v2s to display alleles and coverage. The sequence noise was divided into several categories: noise at allele position, noise at -1 repeat position, and artifact. The average relative percentages of locus cover...
Short tandem repeats (STRs) are short tandemly repeated DNA sequences that involve a repetitive unit of 1-6 bp. Because of their polymorphisms and high mutation rates, STRs are widely used in biological research. Strand-slippage replication is the predominant mutation mechanism of STRs, and the stepwise mutation model is regarded as the main mutation model. STR mutation rates can be influenced ...
Abstract Population studies were carried out on the Y-specific short-tandem-repeat (STR) polymorphisms DYS19, DYS385 I+II, DYS389 I+II, DYS390, DYS391, DYS392, and DYS393 in population samples from North India, Turkey and West Germany. In the German population, a highly unusual haplotype was observed. Sequence analysis revealed, that the variant allele DYS392*11.1 was caused by an insertion of ...
Identification of the short tandem repeats in DNA sequences is a challenging problem for the scientists and engineers in the current era. The detection of the short tandem repeats is also an important part of gene annotation and also it is useful to identify the various hereditary diseases and human identity, etc. The several methods have been developed to find the short tandem repeats, and the...
Y-short tandem repeats (STRs) are located in the nonrecombining part of the Y-chromosome. Its genetic characteristics are helpful to paternity testing. The male lineage can be pursued over several generations. Since an overwhelming majority of rape or sexual assault cases involve male suspects, these markers proved to be very useful with mixed stains. Routine casework performed in our laborator...
Short tandem repeat (STR) variants are highly polymorphic markers that facilitate powerful population genetic analyses. STRs are especially valuable in conservation and ecological genetic research, yielding detailed information on population structure and short-term demographic fluctuations. Massively parallel sequencing has not previously been leveraged for scalable, efficient STR recovery. He...
Background: Quantitative fluorescence-polymerase chain reaction (QF-PCR) is an inexpensive and accurate method for the prenatal diagnosis of aneuploidies that applies short tandem repeats (STRs) as a chromosome-specific marker. Despite its apparent advantages, QF-PCR is not applicable in all cases due to the presence of uninformative STRs. This study was carried out to investigate the efficienc...
In forensic analysis of DNA samples, short tandem repeat (STR) regions in the genome are selectively amplified with PCR to subsequently determine which alleles are present. The DNA polymerase used to amplify STRs with PCR is known to ‘slip’ occasionally, which results in an additional PCR product having one repeat unit more or less than the original allele. These so-called ‘stutter products’ ma...
Allele frequencies for 11 short tandem repeats (STRs) loci (CSF1PO, TPOX, TH01, F13A01, FESFPS, vWA, D16S539, D7S820, D13S317, F13B and LPL) were obtained from a sample of 225 unrelated individuals born in the Entre Ríos state of Argentina.
Cancer transmission from a donor organ to transplant recipient is rare but not infrequently fatal event. We report case of lung cancer deceased 2 kidney recipients. Approximately 1 year after uneventful transplantation, both recipients developed acute failure. Computed tomography imaging abdomen and pelvis for showed masses in the transplanted kidneys along with innumerable livers. Pathologic e...
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