INTRODUCTION Currently alpha1-adrenoceptor blockers (AB) are widely used as first-line therapy to improve lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). We compared the efficacy and safety profile of tamsulosin, alfuzosin and silodosin in LUTS due to BPH. MATERIAL AND METHODS Consecutive consenting male patients (N = 269) undergoing medical management ...

correspondence: steven A Kaplan institute for Bladder and Prostate health, Weill cornell Medical college, cornell University, F9 West, Box 261, 525 east 68th street, new York, nY 10065, UsA Tel +1 212 746 4811 Fax +1 212 746 5329 email [email protected] Objective: The uroselective α-blocker silodosin significantly improved International Prostate Symptom Score (IPSS) in two 12-week, double...

background: premature ejaculation (pe) is the most common sexual disorder in men and studies reported prevalence up to 30% (1, 2). pe is not a life-threatening medical condition but it influences the quality of life (qol). objectives the aim of this study was to compare the efficiency, and safety of alpha blocker drugs in the treatment of patients with premature ejaculation (pe). additionally w...

conclusions silodosin use prior to vcug confers a statistically significant increase in bladder neck opening and visualization of posterior urethra. results in group a 19 out of 20 patients were able to achieve satisfactory bladder neck opening while in group b 10 out of 15 patients were able to achieve bladder neck opening. patients and methods patients were divided into two groups a and b con...

OBJECTIVES To assess the impact of urinary symptoms associated with benign prostatic hyperplasia and its treatment with silodosin, on quality of life (QoL) and sexual function, depending on age, severity of symptoms, time on treatment and prostate size. MATERIAL AND METHODS A cross-sectional, observational study was conducted in 305 urology practices all around Spain. Socio-demographic and cl...

OBJECTIVES To understand the mechanisms underlying ejaculation dysfunction caused by α1A-adrenocetor (AR) antagonists, the effects of α1A-AR antagonists on the contractile responses of the seminal vesicle were investigated. METHODS Isolated seminal vesicles from guinea pigs were cannulated and pressurized, and the changes in the intraluminal pressure were recorded. Periodic applications of el...

Introduction Our aim was to contribute a study that includes a higher patient population to the limited number of studies comparing tamsulosin and silodosin in the treatment of distal ureteral stones. Material and methods Patients who presented with renal colic to the urology emergency clinic and were diagnosed with ureteral stones and followed-up with conservative treatment between January 201...

Urolithiasis is a significant and worldwide health problem. Ureteral stones account for approximately 20% of urolithiasis cases. 70% of those cases are with location of stone in the distal 1/3 rd of ureter hence known as Distal Ureteral Stones (DUS) or Lower Ureteral Stones (LUS). Recently certain drugs have been used as supplement for observation in an effort to improve spontaneous stone expul...