introduction: in this study the evaluation of a platelet-based maximum penalized likelihood estimation (mple) for denoising spect images was performed and compared with other denoising methods such as wavelets or butterworth filtration. platelet-based mple factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to poisson n...

  Introduction: Poor sensitivity and poor signal to noise ratio because of low injected thallium dose and presence of scattered photons are the main problems in using thallium in scintigraphic imaging of the heart. Scattered photons are the main cause of degrading the contrast and resolution in SPECT imaging that result in error in quantification. Thallium decay is ve...