the problem of designing a set of routes with minimum cost to serve a collection of customers with a fleet of vehicles is a fundamental challenge when the number of customers to be dropped or picked up is not known during the planning horizon. the purpose of this paper is to develop a vehicle routing problem (vrp) model that addresses stochastic simultaneous pickup and delivery in the urban pub...

a partial least squares (pls) calibration model was developed for the simultaneous spectrophotometricdetermination of pb (ιι), cu (ιι) and ni (ιι) using xylenol orange as a chromogenic reagent. the parameterscontrolling behavior of the system were investigated and optimum conditions were selected. the calibrationgraphs were linear in the ranges of 0.0–9.091, 0.0–2.719 and 0.0–2.381 ppm for lead...

a simple, accurate and precise hptlc- densitometry method for the simultaneousdetermination of abacavir, lamivudine and zidovudine in pharmaceutical tablet has beendeveloped. separation of tablet components was performed on aluminum backed hptlc plates(silica gel 60 f254 20×20 cm with 0.2 mm thickness, camag, muttenz, switzerland ) usingmethanol : chloroform : acetonitrile (4 : 8 : 3 v/v). good...

h-point standard addition method (hpsam) with simultaneous addition of both analytes in nonaqueous solution was applied for determination of levonorgestrel (lev) and ethinyl estradiol (ee)  in ld and hd tablets. the results showed that, simultaneous determination could be performed with the ratio 1 to 5 of lev-ee. the lod for lev and ee were obtained 5.1×10 -7 and 9.6×10 -7 m, respectively, and...

We present a Chandra ACIS-I X-ray observation of the region near the Herbig early-Be star MWC 297, where we detect a tight group of point X-ray sources. These are probably physically associated to MWC 297, because of their obvious clustering with respect to the more scattered field-source population. These data are compared to earlier ASCA data with much poorer spatial resolution, from which th...

The number of publications considering Narrow-Line Seyfert 1 galaxies has increased dramatically in recent years. Especially after the launch of the X-ray missions ROSAT and ASCA, Narrow-Line Seyfert 1s have become very popular. In these proceedings I will give an overview of how they are distributed over the electromagnetic spectrum. I will describe what we know about them at radio, infrared, ...

simultaneous dislocation of both interphalangeal (ip) joints of same finger is a highly uncommon finding. and dislocation of metacarpophalangeal (mcp) joint along with interphalangeal joints of thumb are reported in literatures if, scarcely. here we are reporting the three cases, comprising of double dislocation of ip joints in little finger in two patients and simultaneous mcp and ip joint dis...

Background: Celiac disease is a common autoimmune disorder that is diagnosed based on clinical case identification, serological screening, and duodenal histology. However, the existence of mild clinical forms, such as seronegative cases with patchy atrophy and potential celiac disease, can make it difficult to determine a definitive diagnosis. The seronegative patients with celiac disease can i...