MITZNER, WAYNE. Hepatic outJrow resistance, sinusoid pressure, and the vascular waterfall. Am. J. Physiol. 227(3): 513-519. 1974.The pressure-flow characteristics of the hepatic common outflow resistance were determined in five anesthetized dogs. These curves were shown to be nearly linear in the range of normal flows, but exhibited a moderate convexity toward the pressure axis at low flows. Th...

The function of the endothelial isoform of nitric oxide synthase (eNOS) and production of nitric oxide (NO) is altered in a number of disease states. Pharmacological approaches to enhancing NO synthesis and thus perhaps endothelial function could have substantial benefits in patients. We analyzed the effect of cicletanine, a synthetic pyridine with potent vasodilatory characteristics, on eNOS f...

The methods of finite-time thermodynamics are used to find the optimal time path of an Otto cycle with friction and heat leakage. Optimality is defined by maximization of the work per cycle; the system is constrained to operate at a fixed frequency, so the maximum power is obtained. The result is an improvement of about 10% in the effectiveness (second-law efficiency) of a conventional near-sin...

Experimental open-loop studies [1] indicate that when a sinusoidal pressure function is forced onto the arterial baroreceptors, a sinusoidal oscillation is reflexly transferred on to R-R interval and arterial pressure, with a rapid fall of gain with increasing oscillatory frequencies. Sleight et al. [2] addressed this issue in man with an elegant approach employing frequency domain analysis. In...

This paper proposes a novel method of speech enhancement that moves away from conventional filtering-based methods and instead aims to reconstruct clean speech from a set of speech features. Underlying the enhancement system is a speech model which at present is based on a sinusoidal model. This is driven by a set of speech features, comprising voicing, fundamental frequency and spectral envelo...

1 November 2001 Alternating Current Theory J R Lucas An alternating waveform is a periodic waveform which alternate between positive and negative values. Unlike direct waveforms, they cannot be characterised by one magnitude as their amplitude is continuously varying from instant to instant. Thus various forms of magnitudes are defined for such waveforms. The advantage of the alternating wavefo...

Detection and modulation rate discrimination were measured in cochlear-implant users for pulse-trains that were either sinusoidally amplitude modulated or were modulated with half-wave rectified sinusoids, which in acoustic hearing have been used to simulate the response to low-frequency temporal fine structure. In contrast to comparable results from acoustic hearing, modulation rate discrimina...

-The average density of randomly placed dots was modulated according to a spatial sinusoid and estimates were made of the signal/noise ratio (d’) of the sensory representation of the pattern from subjects’ responses. This was compared with the signal/noise ratio of the targets, and the results are expressed as the efficiency (F) with which the statistical information in the targets is utilized....

This experiment was an investigation of the ability of listeners to identify the constituents of double vowels (pairs of synthetic vowels, presented concurrently and binaurally). Three variables were manipulated: (1) the size of the difference in F0 between the constituents (0, 1/2, and 6 semitones); (2) the frequency relations among the sinusoids making up the constituents: harmonic, shifted (...

Many communicative behaviors in the animal kingdom consist of performing and recognizing specialized patterns of oscillatory motion. Here we present an approach to the representation and recognition of these oscillatory motions based on the categorical organization of a simple sinusoidal model having very specific and limited parameter values. This characterization is used to specify the types ...