A predominance of small, dense low-density lipoprotein (LDL) is a major component of an atherogenic lipoprotein phenotype, and a common, but modifiable, source of increased risk for coronary heart disease in the free-living population. While much of the atherogenicity of small, dense LDL is known to arise from its structural properties, the extent to which an increase in the number of small, de...

the non-enzymatic glycation of low density lipoprotein (ldl) is a naturally occurring chemical modification of apolipoprotein b as a result of condensation between lysine residues and glucose. glycated ldl is poorly recognized by ldl receptors and initiates different processes that can be considered proatherogenic. thus, ldl glycation may contribute in the increased atherosclerotic risk of pati...

objective(s):resveratrol (res) is a polyphenol compound that has been shown a promising cardioprotective effect. however, some reports have yielded conflicting findings. herein, we investigated the anti-atherosclerotic effects of res in apolipoprotein e (apo e)-deficient mice on a high cholesterol diet. materials and methods: firstly, atherosclerosis was induced by feeding a high cholesterol di...

Small, dense, electronegative low density lipoprotein [LDL(-)] is increased in patients with familial hypercholesterolemia and diabetes, populations at increased risk for coronary artery disease. It is present to a lesser extent in normolipidemic subjects. The mechanistic link between small, dense LDL(-) and atherogenesis is not known. To begin to address this, we studied the composition and dy...

the present study investigated the possibility of replacing salamon with modified shotor diluent (msd) and egg yolk (ey) with low density lipoprotein (ldl) for chilled storage of ram semen. good quality semen (>80% progressive forward motility (pfm) of sperm) from 3 fertile rams was collected using an artificial vagina and pooled for each experiment. low density lipoprotein was extracted from f...

To test whether lipoprotein lipase or hepatic lipase activities are associated with lipoprotein subclasses, and to assess the effects of dietary manipulations on these associations, enzyme activities were measured in postheparin plasma (75 U heparin/kg) from 43 healthy men who were randomly allocated to a low-fat (24% fat, 60% carbohydrate) and a high-fat (46% fat, 38% carbohydrate) diet for 6 ...