Potassium bromate (KBrO3), used in both the food and cosmetics industry, and a drinking water disinfection byproduct, is a nephrotoxic chemical and rodent carcinogen. As KBrO3 is primarily an oxidizing compound, reactive oxygen and other species generated from bromate have been held responsible for the genotoxic, carcinogenic and toxic effects. Bromate induces primary DNA oxidative damage, muta...

Abstract This study compared 3 commonly used quenching agents for dechlorinating samples prior to disinfection byproduct (DBP) analysis under typical drinking water sampling conditions a representative suite of chlorination byproducts. Ascorbic acid and sodium sulfite quenched the residual free chlorine below detection within 5 seconds. Ammonium chloride did not quench with up 70% molar excess,...

Addition of H202 has been employed to repress bromate formation during ozonation of bromide-containing source water. However, the addition of H2O2 will change the oxidation pathways of organic compounds due to the generation of abundant hydroxyl radicals, which could affect the removal efficacy of trihalomethane precursors via the combination of ozone and biological activated carbon (O3-BAC). I...

Advanced oxidation with O3 /H2O2 (peroxone) was conducted on pilot plant scale on pre-treated Meuse river water to investigate the conversion of organic micropollutants (OMPs) and the formation of bromate. Fourteen selected model compounds were dosed to the pre-treated river water on a regular basis to assess the efficiency of the peroxone process and to establish the influence of the water mat...

Human hair keratin films were used in order to examine the e#ects of reducing and oxidizing agents. Thioglycolic acid and sodium bromate were employed as reducing and oxidizing agents, respectively. The white and opaque appearance of the keratin films turned transparent as the concentration of thioglycolic acid increased. However, when followed by the oxidizing treatment, the keratin films retu...

In 1938 Brodie and Friedman (1) published a method for the determination of bromide in tissues and biological fluids. Tissues, serum, urine, or spinal fluid was dried and then fused with sodium hydroxide on a sand bath and the melt containing the bromide was dissolved in water. The use of bromide as a measure of the extracellular fluid was demonstrated by Brodie, Brand, and Leshin (2,3). In the...

Potassium bromate used widely in foods has been associated with various complications in humans. However there is paucity of literature on adverse effects on haematological parameters. Thus we decided to carry out an experimental study to determine the effects of potassium bromate on some blood indices using Wistar rats. Twenty (20) male Wistar rats aged 2-3 months obtained from the department ...