in the present work, the interaction of three water soluble porphyrins, tetra (p-trimethyle) ammoniumphenyl porphyrin iodide (tapp) as a cationic porphyrin, tetra sodium meso-tetrakis (p-sulphonatophenyle) porphyrin (tspp) as an anionic porphyrin and manganese tetrakis (p-sulphonato phenyl)porphinato acetate (mntspp) as a metal porphyrin, with dna have been studied by isothermaltitration microc...

The leucocyte data on four malnourished children who died suddenly when high-energy feeding was started were retrospectively analysed. The pretreatment rate constant for sodium efflux in leucocytes was higher and the intracellular sodium concentration lower in this group than in 13 malnourished children who recovered uneventfully with feeding. Two other children with unusual leucocyte electroly...

Vascular endothelium plays a key role in blood pressure regulation. Recently, it has been shown that a 5% increase of plasma sodium concentration (sodium excess) stiffens endothelial cells by about 25%, leading to cellular dysfunction. Surface measurements demonstrated that the endothelial glycocalyx (eGC), an anionic biopolymer, deteriorates when sodium is elevated. In view of these results, a...

Inner C-cyanide addition and subsequent addition of a methoxy group were observed in the reactions of Ni(II) N-confused tetra(p-tolyl)porphyrin with sodium methoxide and DDQ.

Sodium mass balance is primarily dependent on two factors: dietary salt intake and sodium removal during haemodialysis (HD). Salt intake during the interdialysis period is dependent on patient behaviour and is a strong driver of volume overload [1]. The average American consumes ∼149 mmol/day [2]; most Western societies consume between 150 and 250 mmol/day [3]. There is evidence that HD patient...

In order to determine whether serotonergic (5HT) dorsal raphe nucleus (DRN) cells are involved in body sodium status regulation, the effect of a s.c. infusion of either 2 M or 0.15 M NaCl on 5HT DRN neuron firing was studied using single unit extracellular recordings. In separate groups of 2 M and 0.15 M NaCl-infused rats, water intake, oxytocin (OT) plasma concentration, urine and plasma sodiu...

Sikes, Patricia J., Piyu Zhao, David L. Maass, and Jureta W. Horton. Time course of myocardial sodium accumulation after burn trauma: a 31Pand 23Na-NMR study. J Appl Physiol 91: 2695–2702, 2001.—In this study, 23Naand 31Pnuclear magnetic resonance (NMR) spectra were examined in perfused rat hearts harvested 1, 2, 4, and 24 h after 40% total body surface area burn trauma and lactated Ringer resu...

Based on clinical and experimental work two new types of volumetric overload shocks are reported: volumetric overload shock type one and type two depending on the type of fluid causing their induction. Volumetric overload shock type one is induced by sodium-free fluids such as glycine, glucose, mannitol and sorbitol and is characterized with acute dilutional hyponatraemia. Volumetric overload s...

BACKGROUND The optimal control of blood volume without fluid overload is a main challenge in the daily care of intensive care unit (ICU) patients. Accordingly this study focused on the identification of biomarkers to help characterize fluid overload status. METHODS Sixty-seven patients were studied from ICU admission to day 7 (D7). Blood and urine samples were taken daily and sodium and water...