Favipiravir is a synthetic prodrug, which was first discovered while assessing the antiviral activity of chemical agents active against influenza virus in library Toyoma chemicals. It works by inhibiting RNA dependant polymerase (RdRP), an enzyme required for viral replication inside human cells. A simple, rapid, and economic method developed quantitative determination Favipiravirusing spectrof...

background: lymphocyte-dicentric assay is the most generally accepted method for biological dosimetry of overexposed individuals. in this study, the frequency of unstable chromosome aberration in blood lymphocytes was used to estimate radiation dose received by individuals. evaluation of dose using a calibration curve produced elsewhere may have a significant uncertainty therefore, experiments ...

Several extraction steps involved while analyzing metformin in plasma necessitates the need to develop a simple less tedious RP-HPLC method for analysis human saliva.Blank saliva (2 mL) was spiked with 2 mL solution (12.5 µg mL-1) of and 1 (0.5 caffeine as internal standard (IS). The mixture vortex mixed centrifuged at 3000 rpm 10 minutes. A portion resultant injected into HPLC machine (Agilent...

Percission and accurate gas chromatographic method for determination of propionic acid in bakery products was developed. Bakery productswere directly extraction with ethyl acetat phosphoric used acidic. The extract injected to using butyric as internal standard. Calibration curve range 25 – 1000 µg/mL. Coefissien variation (CV) rates spiked produtcs were 1,36% 99,81% (range 96,32 103,61%) accur...

The electrochemical reduction of zanosar was investigated systematically by direct current polarography, cyclic voltammetry, and differential pulse polarography (DPP). A simple DPP technique was proposed for the direct quantitative determination of anticancer drug zanosar in pharmaceutical formulation and spiked human urine samples for the first time. The reduction potential was -0.28 V versus ...

UNLABELLED A gas chromatography mass spectrometry with spike calibration curve method was used to quantify three carbamate pesticides residue in cooked white rice and to estimate the reduction percentage of the cooking process duration. The selected pesticides are three carbamate pesticides including carbaryl and pirimicarb that their MRL is issued by "The Institute of Standards of Iran" and pr...