A 58-year-old man with advanced-stage pancreatic adenocarcinoma presented with fatigue and dyspnea. Examination revealed tachycardia (102 b/min) with mild tenderness in right upper quadrant. His hemoglobin (Hb) was 7.9 g/dL (10 days prior to presentation 12.2 g/dL), International normalized ratio (INR), platelet count was normal, and the stool guaiac test was negative. On admission, abdominal c...

background : breast cancer is a complicated disease and has various clinical manifestations and prognosis. the aim of this study is to make a breast cancer model suitable for basic, preclinical and clinical studies. materials and methods: five virgin bulb/c mice aged 6 weeks and spontaneous murine mammary adenocarcinoma cells (mmac) were used. after anesthesia induction, 1-3 million of mmacs we...

Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor, polycystic sex cord/stromal tumor, and li...

1. Castration of female mice between 15 and 22 days of age entirely prevented the occurrence of spontaneous adenocarcinoma of the breast, while the non-breeding control mice of the same strain showed a tumor incidence of 78.5 per cent. 3 of the spayed animals developed a spontaneous spindle cell sarcoma. This indicates that the influence of the ovary on the development of breast carcinomas is a...

1 World Health Organisation. Dengue hemorrhagic fever: diagnosis, treatment and control. Geneva: World Health Organisation, 1986. 2 Sawaya R, Means ED. Acute spontaneous subdural hematoma. Surg Neurol 1984;21:363-6. 3 Hanakita J, Kondo A, Nishihara K, Yamamoto Y, Kinuta Y. Spontaneous subdural hematoma in patients with advanced cancer report of two cases. Neurol Med Chir Tokyo 1985;25: 568-70. ...

Abstract Tumour lysis syndrome (TLS) is a well-recognised oncological emergency caused by rapid destruction of cancer cells. Despite most commonly occurring in haematological malignancies or following initiation chemotherapy, rarely, it occurs solid tumours without any trigger. Release nucleic acids during cell breakdown produces large amounts uric acid resulting crystallisation within the rena...

The results of experiments in which surgery, cyclophosphamide, and zymosan have been combined as therapy on a spontaneous mammary adenocarcinoma in CD8Fi fe male mice are evaluated. Zymosan, combined with cyclophosphamide and enucleative surgery, significantly enhanced the therapeutic effect. The mechanism of zymo san action as an immune phenomenon mediated by the host is considered. The data f...

Background: Dirty necrosis (Intraacinar necrosis/garland necrosis) is defined as the presence of cell remnants in lumen gland. consisting an eosinophilic mass, which a mass originating from cytoplasm dead cells mixed with nucleus. The nucleus are blue and pink background. results breakdown carcinoma cells, usually accumulate intact tubular glands, may be associated spontaneous events involving ...