AIMS To study if the total glial cell population in the neocortex is intact in subjects with a history of severe alcohol abuse compared to control subjects. Further, to investigate whether the cortical nerve cell nuclei and nerve cell perikarya volumes are the same in chronic alcoholic subjects as in the control subjects. METHODS Using the stereological method, the optical rotator in a vertic...

BACKGROUND Stereology is the study of estimating geometric quantities. When successfully applied, the combination of immunohistochemistry (IHC) and stereology eliminates intra- and interobserver variability for cell type identification. METHODOLOGY/PRINCIPAL FINDINGS We propose a method to validate existing antibody based cell type markers for stereological application. Comparison was made on...

Morphometric reports on animal and human spleen are very few and no studies have been carried out using stereological methods to investigate all of the tissue compartments of the human spleen. Eighteen samples of spleens, which were either surgically removed after traumatic injury or during treatment for early stage carcinoma or gastric ulcer, were investigated. The point-counting method was us...

The present article reviews the relevant stereological estimators for obtaining reliable quantitative structural data from the lungs. Stereological sampling achieves reliable, quantitative information either about the whole lung or complete lobes, whilst minimising the workload. Studies have used systematic random sampling, which has fixed and constant sampling probabilities on all blocks, sect...

1 Proposed Study Stereology, a form of sampling theory, is a group of statistical methods used for estimating properties such as volume and surface area of a three-dimensional object using information only available on a two-dimensional plane section through the object 2, 9]. It has applications in many areas of science, in particular anatomy, geology and materials science 2]. Conceptually, ste...

OBJECTIVE To determine if there is an association between fatty diet induced obesity and spleen enlargement by means of Cavalieri principle, unbiased stereological method and light microscopic examination. METHODS In this study, we used 16 adult female Sprague Dawley rats, weighing between 150-200 g. All animals were obtained from the Ataturk University Experimental Research and Applying Cent...