AIMS AND BACKGROUND Few clinical data exist concerning normal brain tissue tolerance to re-irradiation. The present study evaluated long-term outcome of 22 recurrent glioblastoma patients re-irradiated with radiosurgery or fractionated stereotactic radiotherapy. METHODS Twenty-two patients were treated with radiosurgery (13, 59%) or fractionated stereotactic radiotherapy (9, 41%) for 24 lesio...

background: radiosurgery is a focal brain irradiation technique that delivers, usually in a single session, high dose of ionizing radiation. the presence of lateral electronic disequilibrium and steep dose gradients in small fields demands special attention to the selection of a suitable detector with respect to its size, composition and response. materials and methods : small circular fields w...

The role of stereotactic radiosurgery in the management of recurrent and newly diagnosed brain metastases was evaluated prospectively. From December 1988 to March 1991, 58 lesions in 40 patients were treated with accelerator-based stereotactic radiosurgery. All patients were followed for a minimum of 6 months or to death. The primary purpose was to determine the impact of radiosurgery on local ...

The idea of attempting to eliminate epileptogenic foci by stereotactic means is not novel; it has been pursued since the 1960s. A range of ablation techniques has been used: from simple electrocoagulation to thermo-coupled electrocoagulation or radiosurgery, and, most recently, focused ultrasound. If the results of stereotactic treatment for epilepsy surgery have not been completely convincing ...

Stereotactic radiosurgery is a technique of external irradiation that utilizes multiple convergent beams to deliver a high single dose of radiation to a small volume. In any stereotactic procedure, a coordinate system associated with a stereotactic frame is used both to reference the 10cation of intracranial structures with radiological studies and to direct intervention, such as biopsy, cranio...

A 77-year-old female presented with a rare cavernous sinus cavernous hemangioma with extension to the sella turcica, neuroradiologically mimicking nonfunctioning pituitary macroadenoma. The lesion was partially removed via transsphenoidal surgery, and the histological diagnosis was cavernous hemangioma. After stereotactic radiosurgery using a cyber knife, the lesion decreased in size. Stereotac...

Address correspondence to: Ricardo H. Brau MD, Professor and Chairman, Section of Neurological Surgery University of Puerto Rico Medical Sciences Campus / Section of Neurosurgery PO Box 365067, San Juan, Puerto Rico 00936. Tel: (787) 765-8276 • Email: [email protected] Historically, the treatment for most intracranial pathologies has included medical management, surgery, radiotherapy and recentl...

Vestibular schwannomas are slow-growing, benign tumours. Microsurgery has been the standard treatment for vestibular schwannoma over the past 30 years. Following the introduction of stereotactic radiosurgery for the treatment of vestibular schwannoma in 1969, its increasing use worldwide had led to its acceptance by many as a safe and efficient alternative to microsurgery. The primary advantage...

The best treatment approach for solitary brain metastasis is not well defined and there is no consensus on this issue. It is still being debated whether patients with isolated brain metastasis should undergo surgical resection or stereotactic radiosurgery, and which patients should receive adjuvant whole brain radiotherapy. The median survival in patients with single or multiple metastatic lesi...

Stereotactic radiosurgery (SRS) provides excellent control in the treatment of brain metastases (BM). The use of newer, targeted and immunotherapy treatments have resulted in improved overall survival in patients even with an extensive metastatic disease. Hence, it is increasingly important to consider the potential for late toxicities like radiation-induced necrosis (RN) of the brain. We prese...