AIM Stevens Johnson syndrome and toxic epidermal necrolysis are severe acute mucocutaneous diseases. In this study, we evaluated the clinical aspects of Steven Johnson syndrome, toxic epidermal necrolysis and Stevens-Johnson syndrome/toxic epidermal necrolysis overlap patients who admitted to our clinics in the last five years. MATERIAL AND METHODS Eleven patients diagnosed as Stevens-Johnson...

Adverse cutaneous reactions are rare side effects of serotonin-selective reuptake inhibitors (SSRIs) (Lamoreux et al. 2006). The dermatological side effects include rashes, erythema multiforme minor, erythema multiforme major or Steven Johnson syndrome, and toxic epidermal necrolysis (Lamoreux et al. 2006; Mockenhaupt et al. 2008; Levi et al. 2009). Erythema multiforme is a dermatological condi...

BACKGROUND Drug hypersensitivity syndrome (DHS) can present in several clinical forms ranging from simple maculopapular skin rash to severe bullous reactions and multi-system dysfunction. Genetic analysis of DHS patients has revealed a striking association between carbamazepine (CBZ)-induced severe bullous reactions, such as Steven-Johnson Syndrome, and toxic epidermal necrolysis in individuals...

A paediatric patient treated for acute lymphoblastic leukaemia developed cerebral abscesses caused by Aspergillus fumigatus. After surgical draining voriconazole treatment was started. The patient developed a Steven-Johnson syndrome and treatment was switched to L-AmB. The patient developed no new fungal lesions and L-AmB treatment was continued until the end of the therapy. Complete remission ...