drugs are an important cause of stevens–johnson syndrome(sjs) in about 95% of reports. 100 drugs have been reported as causes of sjs or toxic epidermal necrolysis (ten). there are very few reports of sjs due to use of diclofenac. in this report we present a 65 year old lady who developed sjs after usage of diclofenac suppository.

Stevens-Johnson syndrome has been an acute, usually self-limiting disease of the skin and mucous membranes. This case report has presented an evidence of the development Stevens - Johnson syndrome associated with combination chemotherapy administration of 5FU, gemcitabin and cisplatin in a patient with biliary tract cancer. Our case was a 54-year-old woman patient, a case of biliary tract cance...

century exceeds natural variability, and thus some of it may be due to anthropogenic carbon dioxide (Stevens, “Experts confirm human role in global warming,” New York Times, Sept. 10, 1995, page 1). This weak claim, unfortunately, is based on the assumption that variability in models is the same as variability in nature. This is not widely believed. Although the scientific statement of this pro...

Non-steroidal anti-inflammatory drugs are commonly prescribed in dental practice after minor oral surgical procedures such as tooth extraction. Diclofenac sodium is one of the non-steroidal antiinflammatory drugs widely used for pain relief in dentistry. Although adverse reactions to these drugs are rare, at times they can cause a life-threatening phenomenon. Stevens-Johnson syndrome is one suc...

OBJECTIVE To assess the type of severe skin reactions caused by valdecoxib treatment. DESIGN Case registry of severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis. SETTING All hospitals in Germany that treat patients with severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis. PATIENTS Five case notifications of Stevens-Johns...

The study of overconvergent cohomology, initiated by Pollack and Stevens in the setting classical modular forms, has now been used to construct p-adic L-functions a number settings. method is conceptual very closely related recent constructions eigenvarieties Ash–Stevens, Urban Hansen. In this note, we give an exposition ideas behind use cohomology constructing L-functions, it attached base-cha...

Stevens-Johnson syndrome is a severe disease which is characterized by fever and mucocutaneous lesions. It has also been described as a small airway compromise in the form of bronchiolitis obliterans. We report a 22-year-old male patient with Stevens-Johnson syndrome due to antibiotic and antiepileptic drug treatment for brain abscess. After the improvement of mucocutaneous lesions, he went to ...

Lamotrigine is an antiepileptic drug used for the treatment of epilepsy, bipolar disorder and numerous off-label uses. The development of rash significantly affects its use. The most concerning of these adverse reactions is Stevens-Johnson syndrome/toxic epidermal necrolysis. We performed a systematic review of randomized controlled trials using lamotrigine as a monotherapy to quantify the inci...

A tandem rhodium-catalyzed Bamford-Stevens/Claisen rearrangement is presented. The tandem reaction uses Eschenmoser hydrazones for the in situ generation of non-carbonyl-stabilized diazo alkanes, which are presumably intercepted by Rh(II) catalysts to induce a 1,2-hydride migration. This sequence provides high levels of stereocontrol for the generation of simple acyclic (Z)-enol ethers. These e...