Stevens-Johnson syndrome is characterized by generalized exanthema associated with high fever, catarrhal symptoms and mucositis. Various etiologies have been implicated, particularly numerous medications and certain agents of atypical pneumonia. Stevens-Johnson syndrome leads to death in up to 5% of cases. We describe the case of a 30-year-old woman with bilateral atypical pneumonia accompanied...

A 13-year-old boy was brought to the emergency department (ED) with a generalized itchy rash of 2 days' duration. For the past 3 days, he had dry, itchy eyes with a purulent discharge (Figure 1) and nonbilious emesis 2 or 3 times per day, with some blood streaks in the vomitus on the third day of illness. Chills developed on the third day, but the patient's temperature was not measured. His lip...

Lamotrigine is an antiepileptic drug used for the treatment of epilepsy, bipolar disorder and numerous off-label uses. The development of rash significantly affects its use. The most concerning of these adverse reactions is Stevens-Johnson syndrome/toxic epidermal necrolysis. We performed a systematic review of randomized controlled trials using lamotrigine as a monotherapy to quantify the inci...

Las urgencias dermatológicas son poco frecuentes, pero refiere a manifestaciones clínicas cutáneas que deben ser atendidas de forma inmediata. Existen pocas patologías pueden considerarse como dentro esta rama, en este artículo se describirán dos interés; la Eritrodermia exfoliativa y el Síndrome Stevens Johnson, tratarán los temas como; etología, clínicas, sus tratamientos.
 La eritroderm...

A new 10 year surface mass balance (SMB) record of Hurd and Johnsons Glaciers, Livingston Island, Antarctica, is presented and compared with earlier estimates on the basis of local and regional meteorological conditions and trends. Since Johnsons is a tidewater glacier, we also include a calving flux calculation to estimate its total mass balance. The average annual SMB over the 10 year observa...

The genus Dunaliella is a halotolerant microalgae are common in hypersaline environments. Additionally, different species of Dunaliella can accumulate significant amounts of valuable fine chemicals such as carotenoids, glycerol, lipids, vitamins, minerals and proteins. Modified Johnsons medium is widely used for growing Dunaliella species, however, without air supplement the growth of algae was...

Drugs are an important cause of Stevens–Johnson syndrome(SJS) in about 95% of reports. 100 drugs have been reported as causes of SJS or toxic epidermal necrolysis (TEN). There are very few reports of SJS due to use of diclofenac. In this report we present a 65 year old lady who developed SJS after usage of diclofenac suppository.

OBJECTIVES The aims of this review are to summarize the definitions, causes, and clinical course as well as the current understanding of the genetic background, mechanism of disease, and therapy of toxic epidermal necrolysis and Stevens-Johnson syndrome. DATA SOURCES PubMed was searched using the terms toxic epidermal necrolysis, Stevens-Johnson syndrome, drug toxicity, drug interaction, and ...

Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, acute conditions, potentially life-threatening, immune-mediated often unpredictable.
 Characteristic for SJS TEN is necrosis of the epidermis mucous membranes, caused by extensive death keratinocytes. These syndromes considered hypersensitivity reactions. They most drugs. There have also been reports / being infe...