نتایج جستجو برای: stirred tank

تعداد نتایج: 17593  

2013
Frédéric Delouvroy Guillaume Le Reverend Boris Fessler Gregory Mathy Mareike Harmsen Nadine Kochanowski Laetitia Malphettes

Introduction Bio-pharmaceutical industries face an increasing demand to accelerate process development and reduce costs. This challenge requires high throughput tools to replace the traditional combination of shake flasks and small-scale stirred tank bioreactors. A conventional and widely used process development tool is the stirred tank reactor (STR) ranging from approximately 1L to 10L in wor...

Journal: :DEStech Transactions on Engineering and Technology Research 2019

Journal: :CoRR 2012
Piyush Shrivastava

this paper presents a predictive control strategy based on neural network model of the plant is applied to Continuous Stirred Tank Reactor (CSTR). This system is a highly nonlinear process; therefore, a nonlinear predictive method, e.g., neural network predictive control, can be a better match to govern the system dynamics. In the paper, the NN model and the way in which it can be used to predi...

Journal: :Cytotechnology 2014
Eutimio Gustavo Fernández Núñez Jaci Leme Letícia de Almeida Parizotto Wagner Antonio Chagas Alexandre Gonçalves de Rezende Bruno Labate Vale da Costa Daniela Cristina Ventini Monteiro Vera Lucia Lopes Boldorini Soraia Attie Calil Jorge Renato Mancini Astray Carlos Augusto Pereira Celso Pereira Caricati Aldo Tonso

This work focused on determining the effect of dissolved oxygen concentration (DO) on growth and metabolism of BHK-21 cell line (host cell for recombinant proteins manufacturing and viral vaccines) cultured in two stirred tank bioreactors with different aeration-homogenization systems, as well as pH control mode. BHK-21 cell line adapted to single-cell suspension was cultured in Celligen withou...

Journal: :Journal of mathematical biology 1999
R Happel P F Stadler

The dynamics of a network of autocatalytically replicating species in a continuously stirred tank reactor can be described by a replicator equation in the limit of small flux rates.

Journal: :Journal of Colloid and Interface Science 1985

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