BACKGROUND The WHO suggested that governments stockpile, as part of preparations for the next influenza pandemic, sufficient influenza antiviral drugs to treat approximately 25% of their populations. Our aim is two-fold: first, since in many countries the antiviral stockpile is well below this level, we search for suboptimal strategies based on treatment provided only to an age-dependent fracti...

This paper explores the problem of medical stockpiling at hospitals in preparing for a flu pandemic. Taking into account the uncertain demand that may occur under various possible pandemic scenarios, we consider the problem of determining the stockpile quantity of one critical medical item. We take a game theoretical approach in order to capture any mutual aid agreement that a group of hospital...

Showcasing examples of the capabilities that National Nuclear Security Administration national laboratories and sites bring to the Stockpile Stewardship Program (SSP) is one of the key intents of the Stockpile Stewardship Quarterly (SSQ). SSQ articles celebrate representative successes of our programs that are made possible by the incredibly talented staff that contributes to these efforts. Thi...

To the Editor: The possible use of smallpox virus as a weapon by terrorists has stimulated growing international concern and led to a recent review by the World Health Organization of the global availability of smallpox vaccine. This review found approximately 60 million doses worldwide, with little current vaccine manufacture, although limited vaccine seed remains available (1). Ongoing discus...

Plants must respond appropriately to a broad array of abiotic and biotic factors in the attempt to accumulate nutrient reserves and reach reproductive maturity. To complicate matters, their stockpile of nutrients makes them prime targets for pathogen attack. Phytopathogenic bacteria, fungi, and viruses all make raids on the stockpile, yet most plants are able to remain disease free. Plants have...

Kegiatan pertambangan batubara selain berdampak positip bagi peningkatkan perekonomian dan menyerap tenaga kerja, juga negatip berupa pencemaran lingkungan. Aktifitas tersebut diantaranya yaitu penyimpanan sementara (stockpile) batubara. Stockpile ketika terpapar hujan menyebabkan unsur yang terkandung di akan terlarut menjadi ion-ion akhirnya terbawa oleh aliran air, hal ini mempengaruhi ku...

Public health agencies across the globe are working to mitigate the impact of the 2009 pandemic caused by swine-origin influenza A (H1N1) virus. Prior to the large-scale distribution of an effective vaccine, the primary modes of control have included careful surveillance, social distancing and hygiene measures, strategic school closures, other community measures, and the prudent use of antivira...

Public health agencies across the globe are working to mitigate the impact of the 2009 pandemic caused by swine-origin influenza A (H1N1) virus. Prior to the large-scale distribution of an effective vaccine, the primary modes of control have included careful surveillance, social distancing and hygiene measures, strategic school closures, other community measures, and the prudent use of antivira...