A 38−year−old Chinese woman presented to our hospital, complaining of a 3−month history of black stool passage and dizzi− ness. Laboratory test results included he− moglobin, 40 g/L (normal: 120 ±160 g/L); red blood cell count, 2.08 ” 1012/L (4.0± 5.5 ” 1012/L); white cell count, 15.48 ” 109/ L (4.0 ± 10.0 ” 109/L); eosinophils, 30.1 % (0.5 %± 5 %); platelet count, 424 ” 109/L (100± 300 ” 109/L...

Several new fecal occult blood tests have advantages over older ones when used for colorectal cancer screening. Fecal immunochemical tests can detect antibodies to human globin in the stool and can be used without the dietary restrictions needed with traditional guaiac tests. Although colonoscopy is often considered the gold standard, we hope that these new tests will allow more people to be sc...

Colorectal cancer (CRC) has a long premalignant phase and relatively slow progression from organ defined invasive disease to local and distant metastatic disease and as such there is ample opportunity to identify patients at a curable stage (1). Current tests are either non-specific as with faecal occult blood testing (2) or invasive. Analysis of DNA markers in stool represents an attractive al...

Clostridium difficile infection (CDI) is an important health problem with severe morbidity and mortality. In our study, 266 adult patients admitted to the hospital between years 2005 2020, were diagnosed CDI included. The relationship fecal occult blood test (FOBT) was examined, it aimed determine clinical characteristics of risk factors for mortality recurrence in these patients. FOBT found be...

Primary eosinophilic gastrointestinal disease (EGID) is a rare inflammatory disorder characterized by eosinophil infiltration in the gut. EGIDs are sub-grouped as esophagitis (EE), gastroenteritis (EG), and colitis (EC). The least frequent manifestation of EC which affects newborns young adults. An 18-year-old male patient was admitted complaining recurrent epigastric lower abdominal pain, dist...

BACKGROUND Colorectal cancer screening and treatment are rapidly evolving. Aims To reappraise stool-based colorectal cancer screening in light of changing test performance characteristics, lower test cost and increasing colorectal cancer care costs. METHODS Using a Markov model, we compared faecal DNA testing every 3 years, annual faecal occult blood testing or immunochemical testing, and col...

Aktaş S, Ergenekon E, Ünal S, Türkyılmaz C, Hirfanoğlu İM, Atalay Y. Different presentations of Cow's milk protein allergy during neonatal period. Turk J Pediatr 2017; 59: 322-328. Cow`s milk protein allergy (CMPA) is the most common cause of allergy occurring in the first year of life due to infant formula or breast-milk of mothers who are drinking cow`s milk or eating cow's milk products. Mos...

This method for measuring fecal occult blood is based on the heme-catalyzed oxidation of tetramethylbenzidine by H2O2. An aliquot of heated stool homogenate is mixed with acetic acid to chemically separate heme from globin. The heme is extracted into ethyl acetate and reacted with the reagent and H2O2 to produce a green oxidation product. The reaction is followed kinetically for 30 to 60 s at 6...