Tudor P Toma, Onn Min Kon, William Oldfield, Reina Sanefuji, Mark Griffiths, Frank Wells, Siva Sivasothy, Michael Dusmet, Duncan M Geddes, Michael I Polkey . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

Members of the tumor necrosis factor receptor (TNFR) superfamily are important for cell growth and survival. In addition to providing costimulatory signals for cell proliferation, ligation of both TNFR1 and Fas can result in programmed cell death or apoptosis. The underlying mechanism requires an intact 80-aa stretch present in the cytoplasmic tails of both TNFR1 and Fas, termed the death domai...

The early growth response transcription factor Egr-1 controls cell specific responses to proliferation, differentiation and apoptosis. Expression of Egr-1 and downstream transcription is closely controlled and cell specific upregulation induced by processes such as hypoxia and ischemia has been previously linked to multiple aspects of cardiovascular injury. In this study, we showed constitutive...

ID: 34 I. Gremyr, V. Siva, H. Raharjo Division of Quality Sciences, Chalmers University of Technology SE-412 96 Sweden T. N. Goh Department of Industrial & Systems Engineering, National University of Singapore Singapore 117576

BACKGROUND Retinal microvascular traits predict adverse health outcomes. The Singapore I Vessel Assessment (SIVA) software improved automated postprocessing of retinal photographs. In addition to microvessel caliber, it generates measures of arteriolar and venular geometry. Few studies addressed the reproducibility of SIVA measurements across a wide age range. METHODS In the current study, 2 ...

The logic of materialist science fails when observers are considered. How can inanimate matter, governed by xed laws, lead to mind? To bring in consciousness as a separate category like space, time, and matter, as suggested by many physicists and neuroscientists, leads to further paradox. This very issue was considered with great subtlety in the Vedic tradition of India. Here we consider one of...

A multivariate approach based on hierarchical cluster analysis has been proposed to study the pattern of rainfall in different mandals of Visakhapatnam district of Andhra Pradesh. The approach was applied to study the rainfall patterns of 42 mandals based on 25 years of rainfall data of Visakhapatnam district from 1986-2010. The application of hierarchical clustering approaches single linkage, ...