BACKGROUND Attenuation correction (AC) improves the diagnostic outcome of stress-only myocardial perfusion imaging (MPI) using conventional SPECT. Our aim was to determine the value of AC using a cadmium zinc telluride-based (CZT)-SPECT camera. METHODS AND RESULTS We retrospectively included 107 consecutive patients who underwent stress-optional rest MPI CZT-SPECT/CT. Next, we created three t...

Despite recent advances in therapeutic and diagnostic approaches, coronary artery disease (CAD) and its related cardiac disorders represent the most common cause of death in the United States. Nuclear myocardial perfusion imaging (MPI) technologies play a pivotal role in the diagnosis and treatment design for CAD. Recently, in order to develop improved MPI agents for diagnosis of CAD, (99m)Tc-[...

BACKGROUND To evaluate the accuracy of myocardial perfusion imaging (MPI) on a novel cadmium-zinc-thelluride camera in detecting significant coronary artery disease (CAD) in patients with atrial fibrillation (AF). METHODS AND RESULTS Seventy-four subjects with AF submitted to stress-rest MPI and coronary angiography were consecutively enrolled. One hundred and forty-eight patients in sinus rh...

Introduction: The main purpose of this study was to compare transient ischemic dilation (TID) ratios in SPECT-low dose CT and SPECT Myocardial Perfusion Imaging (MPI) by application of different quantitative programs and quantify the possible shift in the upper normal limits of TID ratio in the SPECT-CT MPI. Methods: 149 Patients with low pre-test probability for coronary artery disease (CAD), ...

BACKGROUND Subdiaphragmatic activity can produce subdiaphragmatic-related artifacts, which can degrade the quality of myocardial perfusion imaging (MPI). OBJECTIVES We examined the impact of drinking milk, water, and lemon juice on different subdiaphragmatic-related artifacts by using (99m)Tc-sestamibi myocardial single-photon emission computed tomography (SPECT) in order to determine a feasi...

Background—Because of its brief hemodynamic effects and minor effect on determinants of myocardial oxygen demand, vasodilator stress myocardial perfusion imaging (MPI) can be applied very early after acute myocardial infarction (AMI) for risk stratification, allowing management decisions to be made earlier and thus potentially shortening hospitalization stays, reducing costs, and preventing ear...

OBJECTIVE Anatomic coronary artery disease (CAD) can be determined by coronary angiography (CAG) in patients with normal stress single photon emission tomography (SPET) myocardial perfusion imaging (MPI). Coronary angiography results of patients with negative exercise MPI and the prognosis of these patients (CAG-diagnosed CAD vs. non-CAD) were investigated in the current study. SUBJECTS AND M...

BACKGROUND The purpose of this study was to investigate cardiac events in patients with transient left ventricle (LV) dilation on stress myocardial perfusion single-photon emission computed tomography images (MPI). METHODS AND RESULTS Consecutive patients (n=53, 31 males, mean age 71 years) with transient LV dilation on thallium-201 stress MPI (treadmill: 21, pharmacologic: 32) were followed ...

Introduction: Myocardial perfusion imaging using gated SPECT and phase analysis is an effective tool in evaluation of mechanical dyssynchrony. The purpose of this study was to determine the normal ranges of global and regional phase parameters. Methods: A total of 100 patients with normal resting and stress electrocardiograms, low pretest likelihood for c...

Abstract Background False negative myocardial perfusion images on single-photon emission computed tomography (SPECT) imaging (MPI) is a substantial problem in the interpretation of MPI. To explore possible parameters from gated SPECT that could detected coronary artery disease (CAD) patients with normal images, we retrospectively selected who underwent 2-day Tc-99 m MIBI adenosine stress/rest M...