The hamster intergeniculate leaflet (IGL), part of the circadian rhythm regulatory system, has very extensive interconnections with subcortical visual nuclei. The present investigation describes IGL connections with the hamster diencephalon and telencephalon and compares them with ventral lateral geniculate nucleus (VLG) connections and retinal projections. Connections of the geniculate nuclei ...

Intrinsic connections in the anterior portion of the bed nucleus of the stria terminalis 30 (BNST-A) were studied using patch recordings and ultraviolet (UV) uncaging of glutamate 31 (GU) in vitro. UV light was delivered at small BNST-A sites in a grid-like pattern while 32 monitoring evoked responses in different BNST-A regions. Three sectors were 33 distinguished in BNST-A, using fiber bundle...

It has been suggested that some cortically blind patients can process the emotional valence of visual stimuli via a fast, subcortical pathway from the superior colliculus (SC) that reaches the amygdala via the pulvinar. We provide in vivo evidence for connectivity between the SC and the amygdala via the pulvinar in both humans and rhesus macaques. Probabilistic diffusion tensor imaging tractogr...

N-methyl-D-aspartate (NMDA) receptors are commonly found post-synaptically; they mediate fast excitatory neurotransmission in the central nervous system. In this study, we provide immunocytochemical data supporting the existence of presynaptic NMDA receptors in GABAergic terminals using polyclonal antisera raised against the C-terminus of the NMDAR1 subunit. At the light microscope level, rich ...

King, Bruce M. Amygdaloid lesion-induced obesity: relation to sexual behavior, olfaction, and the ventromedial hypothalamus. Am J Physiol Regul Integr Comp Physiol 291: R1201–R1214, 2006. First published June 15, 2006; doi:10.1152/ajpregu.00199.2006.—Lesions of the amygdala have long been known to produce hyperphagia and obesity in cats, dogs, and monkeys, but only recently have studies with ra...

Neurogenesis in the rat septal region was examined with 3H-thymidine autoradiography. The rats in the prenatal groups were the offspring of pregnant females given two injections of 3H-thymidine on consecutive days in an overlapping series: embryonic day (E) 13 + E14, E14 + E15,. . . E21 + E22. The rats in the postnatal groups were injected in a nonoverlapping series: the day of birth and postna...

3H-Guanidinoethylmercaptosuccinic acid (GEMSA) selectively labels the carboxypeptidase B-like enzyme enkephalin convertase (EC) in rat brain tissue sections. We have used autoradiography with 3H-GEMSA to map membrane-bound EC in the rat forebrain and, in conjunction with lesioning techniques, to localize EC to specific neuronal pathways. The highest levels of EC are in the median eminence. High...

PurposeTo identify variations in white matter tract integrity related to behavioural control response emotional stimuli patients with dissociative seizures (DS) and healthy controls (HC), examine associations illness characteristics psychological trauma history.MethodsTwenty DS 20 HC completed an go/no-go task questionnaires, then underwent diffusion tensor imaging (DTI).ResultsPatients had hig...