structural steel sections are mainly used in beams and columns of building frames. iran national steel industrialgroup is among the oldest and largest producers of beams in iran. it has two beam production lines, namely line630 and line 650. in this study, the mechanical properties of manufactured beams in these production lines werecompared. based on the t-test results, the elongation is signi...

Intrahepatic cholestasis, a clinical syndrome, is caused by excessive accumulation of bile acids in body and liver. Proper regulation of bile acids in liver cells is critical for liver injury. We previously reported the effects of dioscin against α-naphthylisothio- cyanate (ANIT)-induced cholestasis in rats. However, the pharmacological and mechanism data are limited. In our work, the animals o...

BACKGROUND The coagulation cascade has been shown to participate in chronic liver injury and fibrosis, but the contribution of various thrombin targets, such as protease activated receptors (PARs) and fibrin(ogen), has not been fully described. Emerging evidence suggests that in some experimental settings of chronic liver injury, platelets can promote liver repair and inhibit liver fibrosis. Ho...

Intrahepatic cholestasis is a kind of clinical syndrome along with hepatotoxicity which caused by intrahepatic and systemic accumulations of bile acid. There are several crucial generating factors of the pathogenesis of cholestasis, such as inflammation, dysregulation of bile acid transporters and oxidative stress. SIRT1 is regarded as a class III histone deacetylase (HDAC). According to a set ...

Software testing is important, but judging whether a set of software tests are effective is hard. The same problem also appears in the classroom as educators frequently include software testing activities in assignments. While tests can be hand-graded, some educators use objective performance metrics to assess software tests, just as professionals do. The most common measures used at present ar...

Cognitive skills predict academic performance, so schools that improve academic performance might also improve cognitive skills. To investigate the impact schools have on both academic performance and cognitive skills, we related standardized achievement-test scores to measures of cognitive skills in a large sample (N = 1,367) of eighth-grade students attending traditional, exam, and charter pu...

Web-based aptitude tests which are a particular category of aptitude tests can be used for a large number of users to test their competence, knowledge and aptitude with standardised testing methods. The webbased solution is getting more and more important, because of the recent technological advances and low cost, high effectiveness, overall availability, and an easy distribution. We analysed a...