Tirazine based microporous polymeric (TMP) network was found to be an efficient metal-free catalyst for the epoxidation of styrene. The reactions were performed in water as an environmentally benign medium using H2O2 as a green oxidant at ambient temperature. The reaction afforded higher yield with 90% conversion of styrene and 98% selectivity to styrene oxide in 6 h. The triazine based micropo...

UNLABELLED The Atraumatic Restorative Treatment (ART) approach was suggested to be a suitable method to treat enamel and dentine carious lesions in patients with disabilities. The use of a restorative glass-ionomer with optimal mechanical properties is, therefore, very important. OBJECTIVE To test the null-hypotheses that no difference in diametral tensile, compressive and flexural strengths ...

We are the first to report allosterism during styrene oxidation by recombinant CYP2E1 and human liver microsomes. At low styrene concentrations, oxidation is inefficient because of weak binding to CYP2E1 (K(s) = 830 μM). A second styrene molecule then binds CYP2E1 with higher affinity (K(ss) = 110 μM) and significantly improves oxidation to achieve a k(cat) of 6.3 nmol · min(-1) · nmol CYP2E1(-...

 Background: The measurement data regarding the influent and effluent of wastewater treatment plant (WWTP) provides a general overview, demonstrating an overall performance of WWTP. Nevertheless, these data do not provide the suitable operational information for the optimization of individual units involved in a WWTP. A full-scale evolution of WWTP was carried out in this study via a r...

Styrene has been found to be toxic to the respiratory system, and the toxicity of styrene is metabolism-dependent. CYP2E1 is suggested to be one of the cytochrome P450 enzymes responsible for the bioactivation of styrene. Our work focused on the roles of CYP2E1 and epoxide, a metabolite of styrene epoxidation, in the cytotoxicity of styrene. Styrene was found to be more toxic to h2E1 cells than...

Styrene metabolism in styrene-degrading Pseudomonas putida CA-3 cells has been shown to proceed via styrene oxide, phenylacetaldehyde, and phenylacetic acid. The initial step in styrene degradation by strain CA-3 is oxygen-dependent epoxidation of styrene to styrene oxide, which is subsequently isomerized to phenylacetaldehyde. Phenylacetaldehyde is then oxidized to phenylacetic acid. Styrene, ...

OBJECTIVE To review the epidemiologic literature on styrene and cancer. METHODS We reviewed studies of workers exposed to styrene in manufacturing and polymerization, in the reinforced plastics industry, and in styrene-butadiene rubber production. We also reviewed studies of workers monitored for styrene exposure, studies of environmental exposure, community-based case-control studies of lymp...