Thyroiditis should be in the differential for hyperthyroidism when thyroid-stimulating hormone (TSH) is suppressed and T3/T4 levels are elevated. Suspicion of further increased patient can exhibit symptoms such as weight loss, anxiety, feeling feverish, tremors, shaking, sweating. Hyperthyroidism generally classified being overt or subclinical. In following case, had which considered more sever...

Adequate concentrations of thyroid hormones are necessary for bone development and maturation whereas excess concentrations enhance bone turnover and cause osteoporosis [1]. Although this phenomenon is most obvious in patients with overt hyperthyroidism (H) some studies suggest that even mild subclinical hyperthyroidism (SH) is associated with increased bone resorption [2] and accelerated bone ...

Subclinical hyperthyroidism may be defined as the presence of free thyroxine and tri-iodothyronine levels within the reference range and a reduced serum thyroid stimulating hormone (TSH) level. In this review the prevalence of low TSH in the population and health consequences of subclinical hyperthyroidism, for example, effects on heart and bone mass, are discussed. Guidelines for treatment are...

BACKGROUND AND PURPOSE Subclinical hyperthyroidism is associated with adverse cardiovascular events, including stroke and atrial fibrillation. However, its impact on functional outcome after stroke remains unexplored. METHODS A total of 165 consecutively recruited patients admitted for ischemic stroke were included in this observational prospective study. Blood samples were taken in the morni...

BACKGROUND Subclinical hypothyroidism has been associated with depressive symptoms in cross-sectional studies, but prospective data and data on subclinical hyperthyroidism are scarce. METHODS In the Leiden substudy of the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER), thyroid-stimulating hormone and free T4 levels were measured at baseline and repeated after 6 months in ad...

Subclinical hyperthyroidism is defined by low or undetectable serum thyroid-stimulating hormone levels, with normal free thyroxine and total or free triiodothyronine levels. It can be caused by increased endogenous production of thyroid hormone (as in Graves disease or toxic nodular goiter), administration of thyroid hormone for treatment of malignant thyroid disease, or unintentional excessive...

Management of subclinical hyperthyroidism (low TSH and normal thyroid hormones) is controversial. Knowledge of its causes, clinical context and associated morbidity is required. It is recommended to follow six steps in exploration and treatment: 1) confirmation, 2) estimation of severity, 3) cause assessment, 4) study of complications, 5) balance whether treatment is needed and 6) if necessary,...

OBJECTIVE The treatment of subclinical hyperthyroidism is controversial because the natural history is uncertain. We undertook a retrospective study to examine the natural history of endogenous subclinical hyperthyroidism. METHODS Between 2002 and 2006, we identified 116 patients with thyroid-stimulating hormone (TSH) concentrations <0.4 microIU/mL but normal free thyroxin and triiodothyronin...

Several in-vivo studies have shown a procoagulant state in both overt and subclinical hyperthyroidism and in subclinical hypothyroidism. Insofar, no clinical studies have ever evaluated the relationship between thyroid dysfunction and clinically deep venous thrombosis (DVT). A pilot cross-sectional study aimed at assessing the frequency of overt and subclinical thyroid dysfunction patients with...