OBJECTIVE To investigate the effect of vascular endothelial growth factor (VEGF) injection into the testes on spermatogenesis and apoptosis in a varicocele-induced adolescent rat model. SETTING University hospital urology research laboratory. ANIMAL(S) Six-week-old male Wistar rats (n = 32). INTERVENTION The rats were divided into six groups: control group (n = 6), sham operated group (n ...

generated in response to oxidative stress – play an important role in cell protection by performing functions like catalyzing the conjugation of a large variety of endogenous and exogenous compounds including ROS, carcinogenic compounds, and their metabolites. A previous study clearly demonstrated an abundance of GSTs in the male reproductive tract and showed that GSTs play important roles in t...

The prevalence of varicocele is 7% and 10–25% in pre pubertal and post pubertal males, respectively [1]. Varicoceles are found in 21–41% of men with primary infertility and 75–81% of those with secondary infertility. Physical examination of varicocele has a sensitivity and specificity of around 70%. The Color Doppler ultrasound (7MHz) has sensitivity of 50% and specificity of 90%. A pencil prob...

INTRODUCTION The aim of this study was to evaluate varicocele patients' brothers to determine whether they are at a higher risk of varicocele than the general population of men. MATERIALS AND METHODS A total of 56 patients with varicocele and their 131 brothers (> 16 years old) were evaluated. The brothers had no complaints of infertility, pain, or cosmetic problems. They were all examined fo...

BACKGROUND Varicocele is characterized by abnormal tortuosity and dilatation of the veins of the pampiniform plexus within the spermatic cord and is one of the causes of male infertility. This study aimed to evaluate the differences in biochemical markers and body mass index (BMI) between patients with and without varicocele. METHODS Between January 2004 and June 2009, 102 patients with varic...

Varicocele is one of the most common correctable causes male infertility. can also cause scrotal pain or discomfort. Treatment varicocele proved to have benefits in terms fertility and pain. There are many treatment options for varicocele. This review aims describe procedures determine outcomes, advantages disadvantages each option.

Samenvatting In dit overzichtsartikel wordt de relatie besproken tussen een varicocele, mannelijke subfertiliteit, kans op kind met en zonder behandeling van varicocele na natuurlijke conceptie of geassisteerde voortplanting. Er kort ingegaan verschillende theorieën over pathofysiologie varicocele. Daarnaast worden klinische diagnose overwegingen rond selectie indicatiestelling bij subfertiele ...

Among infertile men, a diagnosis of unilateral varicocele is made in 90% of varicocele cases and bilateral in the remaining varicocele cases. However, there are reports of under-diagnosis of bilateral varicocele among infertile men and that its prevalence is greater than 10%. In this prospective study, we aimed to examine the differentially expressed proteins (DEP) extracted from spermatozoa ce...

Background: To investigate difference in intratesticular arterial pulsatility index (PI) and resistance index (RI) between varicocele and healthy testes using power Doppler ultrasonography. Materials and Methods: Patients undergoing scrotal ultrasonography were recruited. PI and RI of the intratesticular artery were measured using a 12-MHz power Doppler ultrasound, and varicocele grades were ob...