Collaborative filtering is an effective recommendation approach in which the preference of a user on an item is predicted based on the preferences of other users with similar interests. A big challenge in using collaborative filtering methods is the data sparsity problem which often arises because each user typically only rates very few items and hence the rating matrix is extremely sparse. In ...

Background and Aim: There is a gap of information on the effect of time, disinfectant, and storage conditions on the dimensional stability of direct post patterns made of self-cure acrylic resins. This study assessed the effect of Deconex® and wet or dry stor-age conditions on the dimensional stability of post patterns made of Duralay and GC acrylic resins. Materials and Methods: Sixty spe...

introduction: the purpose of this study is to evaluate the effects of topical application of honey on the burn of full-thickness skin in rats. materials and methods: 40 adult female rats were divided into two groups and each group was subdivided into control and two experimental subgroups. the experiments were carried out under nitrofurazone anaesthesia. a third degree burn was carried out in t...

Large randomized controlled clinical trials are the gold standard to evaluate and compare the effects of treatments. It is common practice for investigators to explore and even attempt to compare treatments, beyond the first round of primary analyses, for various subsets of the study populations based on scientific or clinical interests to take advantage of the potentially rich information cont...

CLINICAL TRIALS PROVIDE EVIDENCE of effectiveness of treatments as an average for a group of patients, yet, in clinical medicine, we usually wish to apply these results to individuals. Can we simply apply the overall trial result for each patient, or can the result be tailored to individual patients in some way? Consider a hypothetical example: a randomised trial comparing treatments A and B sh...

You are a physicianworking at a regional trauma center. Your unit's committee,which is responsible for standardization of care, is considering using tranexamic acid to treat trauma patients arriving 3 hours after injury. Almost all the informationon this topic is derived fromasingle,blindedtrial that randomizedtraumapatients totranexamic acid or placebo. Theoriginal publication reported that99%...