The GABAA receptor is a ligand-gated ion channel of the Cys-loop family that includes nicotinic acetylcholine, 5-HT3 and strychnine-sensitive glycine receptors. receptor-mediated inhibition within CNS occurs by fast synaptic transmission, sustained tonic temporally intermediate events have been termed 'GABAA, slow' [45]. receptors exist as pentamers 4TM subunits form an intrinsic anion selectiv...

Introduction: There is considerable evidence that glutamate-mediated excitatory neurotransmission plays an important role in mediating the behavioral actions of acutely administered ethanol. The aim of the present study was to investigate the effect of acute ethanol exposure on NR1 subunit of NMDA (n-methyl-d-aspartate) receptor distribution in the cerebral cortex of chick embryo on the 10th...

Brucellosis caused by species of Brucella is among the most prevalent zoonoses with the annual incidence of half a million cases globally. Most parts of Iran are endemic for brucellosis, and the annual incidence of the human and animal brucellosis is still high. At present, there is no safe and protective human vaccine against brucellosis, and the only preventive strategy is animal vaccination,...

bemisia tabaci (gennadius) (hemiptera: aleyrodidae), is one of the most important pest of vegetable and fruit crops. this polyphagous pest has a range of natural enemies including the parasitoid eretmocerus mundus (merect) (hymenoptera: aphelinidae). to determine the molecular profile and taxonomic status of iranian isolates of e. mundus, parasitized b. tabaci samples were collected from cotton...

Hemoglobin is a tetrameric oxygen transport protein in animal bodies. However, there is a paucity of information regarding differences between alpha and beta subunits of hemoglobin in terms of oxygen affinity. The sequential model of Koshland, Nemthy and Filmer (KNF model) has attributed similar affinities to both alpha and beta subunits. The main purpose of the present study is to construct a ...

Poxviruses are enveloped viruses with a linear, double-stranded DNA genome. Viral synthesis is achieved by functional polymerase holoenzyme composed of three essential proteins. For vaccinia virus (VACV) these E9, the catalytic subunit, family B polymerase, and heterodimeric processivity factor formed D4 A20. The A20 protein links to subunit. High-resolution structures have been obtained for VA...

This study was designed with the aim of exploring efficacy RNA polymerase beta subunit, rpoB gene analysis for identification streptomycetes. A characteristic marine environment distinguished by their content streptomycetes were targeted, and two organisms genus Streptomyces isolated in Saudi Arabia. The spp., named isolates EH1 EH2 subjected to regular phenotypic characterization including mor...

high molecular weight (hmw) subunits of wheat glutenin are generally considered as playing a key role in gluten formation and structure, as well as to be closely related to wheat quality. the endosperm storage proteins of 80 synthetic lines and wheat cultivars (triticum aestivum) were fractionated through sodium dodecyl sulfate polyacrylamide gel electrophoresis to determine their high-molecula...