Fast cysteine labelling of peptides promoted by an adjacent arginine has been observed with a standard labelling agent specific for amines, N-succinimidyl 4-[(18)F]fluorobenzoate.

A fluorescent photochromic compound, composed of diarylethene, fluorescein and succinimidyl ester units, was developed for the controllable fluorescent labeling of biomolecules based on a small molecule.

Although proteins consist exclusively of L-amino acids, we have reported that aspartyl (Asp) 58 and Asp 151 residues of aAcrystallin of eye lenses from elderly cataract donors are highly inverted and isomerized to D-b, D-a and L-b-Asp residues through succinimide intermediates. Of these Asp isomers, large amounts of D-band L-b-isomers are present but the amount of D-a-isomer is not significant....

?-Aryl-?-diazoamides were synthesized in two steps under mild conditions. This expeditious route employs Pd-catalyzed C–H arylation of N-succinimidyl 2-diazoacetate to obtain 2-aryl-2-diazoacetates, followed by aminolysis. The ensuing diazo compounds can esterify carboxyl groups aqueous solution, and the ester products are substrates for an esterase. broad scope synthetic enables continued deve...

FGSS118 Reproduction in the 21st Century This course will cover basic human reproductive biology, new and future reproductive and contraceptive technologies, and the ethics raised by reproductive issues. Offering: Crosslisting Grading: A-F Credits: 1.00 Gen Ed Area: NSM-BIOL, NSM-BIOL, NSM-BIOL, NSM-BIOL, NSM-BIOL Identical With: BIOL118, PHIL118, SISP118, BIOL118, PHIL118, BIOL118, PHIL118, BI...

We consider an age-maturity structured model arising from a blood cell proliferation problem. This model is "hybrid", i.e., continuous in time and age but the maturity variable is discrete. This is due to the fact that we include the cell division marker carboxyfluorescein diacetate succinimidyl ester. We use our mathematical analysis in conjunction with experimental data taken from the divisio...