Although adolescents with delinquency are known to have higher-than-average rates of depression or substance use disorder (SUD), research on the topic is inconsistent. It remains unclear weather depression or SUD leads to delinquency, whether delinquency leads to depression or SUD, or whether there is bi-directionality. Utilizing the National Survey of Child and Adolescent Well-Being (Wave I: 2...

Frederico D. Novaes,1 Nicolás Lorente,2 and Jean-Pierre Gauyacq3,4 1Institut de Ciència de Materials de Barcelona, CSIC, Campus de la UAB, E-08193 Bellaterra, Spain 2Centre d’Investigació en Nanociència i Nanotecnologia, CSIC-ICN, Campus de la UAB, E-08193 Bellaterra, Spain 3CNRS, Institut des Sciences Moléculaires d’Orsay (ISMO), Unité de Recherches CNRS-Université Paris-Sud, UMR 8214, Bâtimen...

Co-occurring posttraumatic stress disorder (PTSD) and substance use disorder (SUD) affects multiple domains of functioning and presents complex challenges to recovery. Using data from the National Comorbidity Study Replication, a national epidemiological study of mental disorders (weighted N = 4,883), the current study sought to determine the prevalence of PTSD and SUD, the symptom presentation...

Jean-Pierre Gauyacq,1,2 Frederico D. Novaes,3 and Nicolás Lorente4 1CNRS, Institut des Sciences Moléculaires d’Orsay, ISMO, Unité de Recherches CNRS–Université Paris-Sud, Bâtiment 351, Université Paris-Sud, 91405 Orsay CEDEX, France 2Université Paris-Sud, Institut des Sciences Moléculaires d’Orsay, ISMO, Unité de Recherches CNRS–Université Paris-Sud, Bâtiment 351, Université Paris-Sud, 91405 Or...

We surveyed 205 Veterans Affairs (VA) staff on treatment of posttraumatic stress disorder (PTSD), substance use disorder (SUD), and the combination (PTSD/SUD). The survey was anonymous and VA-wide. PTSD/SUD was perceived as more difficult to treat than either disorder alone; gratification in the work was stronger than difficulty (for PTSD, SUD, and PTSD/SUD); and difficulty and gratification ap...

OBJECTIVES To determine and compare hepatitis C (HCV) screening and testing rates among four groups: those with (i) bipolar disorder [BD group (history of BD but no substance use disorder)]; (ii) substance use disorders [SUD group (history of SUD but no BD)]; (iii) co-occurring disorders [DD group (history of both BD and an SUD)]; and (iv) a control group (no history of either bipolar disorder ...

Personality disorders (PD) and substance use disorders (SUD) are highly comorbid conditions. However, their treatment services are often separated. The aims of this study was to investigate how extensive this separation was prior to a Norwegian health reform (2004) that promoted integration, and to discuss clinical challenges for an integrated treatment of PD and SUD. All patients with a diagno...

Since the outbreak of severe acute respiratory syndrome (SARS) in 2003, the three-dimensional structures of several of the replicase/transcriptase components of SARS coronavirus (SARS-CoV), the non-structural proteins (Nsps), have been determined. However, within the large Nsp3 (1922 amino-acid residues), the structure and function of the so-called SARS-unique domain (SUD) have remained elusive...

J. Oden Laboratoire Charles Fabry, Institut d’Optique, CNRS, Univ Paris Sud, 2 Avenue Augustin Fresnel, 91127 PALAISEAU cedex, FRANCE S. Trebaol Laboratoire Charles Fabry, Institut d’Optique, CNRS, Univ Paris Sud, 2 Avenue Augustin Fresnel, 91127 PALAISEAU cedex, FRANCE P. Delaye Laboratoire Charles Fabry, Institut d’Optique, CNRS, Univ Paris Sud, 2 Avenue Augustin Fresnel, 91127 PALAISEAU cede...

OBJECTIVE This study examined 6-month treatment outcomes among 428 cocaine-dependent outpatients with (n = 34) and without (n = 394) posttraumatic stress disorder (PTSD) in a randomized controlled multisite clinical trial of manual-based psychotherapies for substance use disorder (SUD). METHOD Assessments were completed at baseline and monthly during the 6-month treatment. With longitudinal m...