the aim of this study was to compare the total protein levels in serum of veteran exposure to sulfur mustard (sm) which was used in the iran-iraq war. in this study, 35 patients exposed to mustard gas (case group) and 35 healthy subjects (control group) were evaluated. the total protein concentration was measured by bradford method. the average amount of protein in serum exposure to sulfur must...

Before the 1970s, the United States sometimes disposed of at sea excess, obsolete, or unserviceable munitions, including chemical munitions. Chemical munitions known to have been disposed of at sea included munitions filled with sulfur mustard, a vesicant (i.e., an agent that causes chemical burns or blisters of the skin and mucous membranes). Signs and symptoms of exposure to a mustard agent c...

Introduction: Glutathione S-transferase (GST) is one of the major detoxifiers in alveoli. Polymorphism in GST genes can influence the ability of individuals to suppress oxidative stress and inflammation. The present study was aimed to explore the hypothesis that the genetic polymorphisms of GST T1, M1 and P1 are associated with the severity of the mustard lung in the sulfur mustard-exposed indi...

Strain L mouse fibroblasts growing in vitro were exposed to varying concentrations of nitrogen and sulfur mustards, and the surviving fraction of cells was measured by their ability to form macroscopically visible colonies. Nitrogen mustard required 3 hours but sulfur mustard less than 1 hour to exert maximum killing effect. The mean lethal dose (D37) for nitrogen mustard acting for 1 hour on a...

Sulfur mustard is a chemical agent of high military and terroristic significance. No effective antidote exists, and sulfur mustard can be fairly easily produced in large quantity. Rapid field testing of sulfur mustard is highly desirable. Existing analytical devices for its detection are available but can suffer from low selectivity, laborious sample preparation, and/or the need for complex ins...

PURPOSE In patients with short-term exposure to the sulfur mustard gas, the delayed cellular effects on lungs have not been well understood yet. The lung pathology shows a dominant feature consistent with obliterative bronchiolitis, in which fibroblasts play a central role. This study aims to characterize alterations to lung fibroblasts, at the cellular level, in patients with delayed respirato...

Sulfur mustard, a potent inhibitor of two-stage skin tumorigenesis, appears to act primarily by inactivating initiated cells rather than by suppressing the biochemical response to the promoter ^-O-tetradecanoylphorboMSacetate (TPA). Thus, when the increase of epidermal-dermal p-tosyl-L-arginine methyl ester esterase activity in TPAtreated mice was compared with the response of mice similarly tr...

purpose: to determine any possible correlation between delayed ocular complications with late-onset complications of mustard gas poisoning in other systems including skin, respiratory tract, and immunohematologic system. methods: the study was conducted on 40 chemical war victims in khorasan province, iran. ophthalmologic and dermatologic examinations and spirometry were performed for all patie...

background: despite almost the three decades passed since the chemical attacks of iraqi’s army against the iranian troops, some veterans are still suffering from long-term complications of sulfur mustard (sm) poisoning, including certain skin complaints specially dryness, burning, and pruritus. we thus aimed to evaluate the skin’s water and lipid content in patients with a disability of >25% du...