In the present study, Fe3O4 super paramagnetic nanoparticles were synthesized via co-precipitation of Fe3+ and Fe2+ chloride salts in the presence of ammonia Solution. The product was characterized by Fourier Transform Infrared spectroscopy (FT-IR), Transmission Electron Microscopy (TEM), and zeta–potential particle size distributing methods. The synt...

Abstract This study aimed to modify the biological response of cells to ionizing radiation by combination therapy using radio-sensitizer agent and anticancer drug. Super paramagnetic iron oxide nanoparticles (SPIONs) were prepared and used with gemcitabine (Gem). These two agents were encapsulated simultaneously into poly (D, L-lactic-co-glycolic acid) (PLGA) to form multifunc...

Introduction Endothelial progenitor cells (EPC) are promising candidates for novel stem cell transplantation strategies to treat cardiovascular diseases. Within this study formations of vascular network structures with super paramagnetic iron oxide (SPIO) loaded EPCs were induced, which is an in vitro correlate of the vasculogenesis process [1]. The resulting endothelial network showed to be an...

Introduction: Positive-contrast imaging of super paramagnetic iron oxide (SPIO)labeled cells avoids problems associated with negative contrast such as other signal voids and partial volume effects [1-7]. Many techniques offer 2D imaging with thick slices and long scan times. A fast 3D alternating repetition time (ATR) SSFP [8] method with reliable on-resonant suppression has recently been intro...

Introduction: Iron plays an important role in physiological processes as a trace element. Today, iron oxide nanoparticles have attracted extensive attention due to their super paramagnetic properties and a variety of potential applications in many fields. The main objective of this study was to evaluate in vitro and in vivo toxic effects of the iron oxide nanoparticles on L929 cell line, kid...

Objective(s):Iron oxide nanoparticles have found prevalent applications in various fields including drug delivery, cell separation and as contrast agents. Super paramagnetic iron oxide (SPIO) nanoparticles allow researchers and clinicians to enhance the tissue contrast of an area of interest by increasing the relaxation rate of water. In this study, we evaluate the dependency of hydrodynamic si...

In the past decades, there is a growing interest in the design and synthesis of composite microspheres with a dielectric solid sphere (e.g., silica, polystyrene) covered by metallic and their corresponding metal oxides shell, such as copper[1], gold[2], silver[3,4], iron oxide[5], zinc oxide[6,7], titanium oxide[8,9] and zirconium dioxide[10]. Such materials may exhibit a few unique electrical,...

Magnetic and macro/mesoporous bioactive glasses were synthesized by a one-pot method via a handy salt leaching technique. It was identified to be an effective and simple synthetic strategy. The non-ionic triblock copolymer, poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) (P123), was used as the structure directing agent for mesoporous structure but also as the red...

Liposomes are one of the most promising biomaterial carriers to deliver DNA,(1) proteins, drugs and medicine in human bodies. However, artificially formed liposomes have to satisfy some crucial functions such as: (i) to efficiently carry drugs to targeted systems, (ii) to be biologically stable until they are removed from human body, (iii) to be biodegradable, and (iv) to be sufficiently small ...

Electronic states of iron ion complexes in human blood from patients with melanoma have been investigated by electron paramagnetic resonance (EPR). The measurements were performed at liquid nitrogen temperature (77 K) on an X-band EPR spectrometer. Numerous types of iron paramagnetic centers have been identified. In several kinds of protein complexes exemplified by methemoglobin, transferrin or...