In vitro cell-based assays are widely used during the drug discovery and development process to test the biological activity of new drugs. Most of the commonly used cell-based assays, however, lack the ability to measure in real-time or under dynamic conditions (e.g. constant flow). In this study a multi-parameter surface plasmon resonance approach in combination with living cell sensing has be...

Since its first observation by Wood in 1902 [1,2], the physical phenomenon of surface plasmon resonance (SPR) has found its way into practical applications in sensitive detectors, capable of detecting sub-monomolecular coverage. What is surface plasmon resonance? Wood observed a pattern of ‘‘anomalous’’ dark and light bands in the reflected light, when he shone polarized light on a mirror with ...

The integration of silver and gold nanoparticles with graphene is frequently sought for the realization of hybrid materials with superior optical, photoelectric and photocatalytic performances. A crucial aspect for these applications is how the surface plasmon resonance of metal nanoparticles is modified after assembly with graphene. Here, we used the discrete dipole approximation method to stu...

In the last two decades, surface plasmon resonance (SPR) has evolved from a fairly esoteric physical phenomenon to an optical tool that is widely used in physical, chemical and biological investigations where the characterization of an interface is of interest. Recently, the field of SPR nano-optics has been added where metallic structures on a nanoscale can be designed such that they can perfo...

bacteria by using surface plasmon resonance analysis Sravya Sowdamini Nakka, Johanna Lönn, Carin Starkhammar Johansson, Torbjörn Bengtsson & Fariba Nayeri The Institution for Protein Environmental Affinity Surveys, PEAS Institut AB, Linköping, Sweden Clinical Research Center, School of Health and Medical Sciences, Örebro University, Örebro, Sweden Centre for Oral Rehabilitation, Public Dental H...

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In this review, we explored the fabrication and application of various metallic nanostructures that support localized surface plasmons. Principles and unique characteristics for individual nanopatterning technologies were demonstrated and relevant discussion focused on the process cost, throughput, and possibilities of large-area patterning and mass production. As a potential use of the nanosca...