methylmalonic acidemia (mma) is usually caused by a deficiency of the enzyme methylmalonyl-coa mutase (mcm), a defect in the transport or synthesis of its cofactor, adenosyl-cobalamin (cbla, cblb, cblc, cblf, cbld, and cblx), or deficiency of the enzyme methylmalonyl-coa epimerase. a comprehensive diagnostic approach involves investigations of metabolites with tandem mass spectrometry, organic ...

myelolipoma, a rare benign non-functioning neoplasm, is composed of mature adipose tissue and bone marrow elements. its most common location is adrenal gland; however, extra-adrenal cases have been also reported. it is found in only 0.2% of all autopsies; 96% of the reported cases were detected on postmortem examination. the surgical symptomatic cases having been reported so far are few. in thi...

Though the lumbar disc syndrome is a costly and ubiquitous affliction, effective evaluation of the disease process has been confounded by major unaddressed methodological short falls. Prominent difficulties include: inattention to the clinical boundaries of the syndrome, neglected co-morbid disease processes, comparison of unequal treatment groups and premature clinical data extrapolation, inad...

methods allplex gi-virus assay was developed to detect pathogens causing viral gastroenteritis, one of the major diseases caused by rna viruses. this one-step multiplex real-time polymerase chain reaction (pcr) based on the mudt technique permits simultaneous amplification and detection of target nucleic acids of norovirus gi, norovirus gii, rotavirus a, adenovirus f, astrovirus, and sapovirus ...

introduction: using pan or selective computed tomography (ct) scan in management of multiple trauma patient is a matter of debate. therefore, the present study was designed aiming to compare the findings of pan and selective ct scans in management of multiple trauma patients. method: this is a prospective cross-sectional study, on patients presented to the emergency department (ed) of shohadaye...

Surgical site infections are the most common complication of surgery in the United States. Of surgeries in women of reproductive age, hysterectomy is one of the most frequently performed, second only to cesarean birth. Therefore, prevention of surgical site infections in women undergoing gynecologic surgery is an ideal topic for a patient safety bundle. The primary purpose of this safety bundle...