Syphilis, a chronic multisystem disease, is caused by a spirochete, Treponema pallidum. Clinical presentation may expand to several stages including primary, secondary and latent syphilis, which may present as early or late syphilis. Nephrotic syndrome and acute hepatitis are well-known complications of secondary syphilis. To the best of our knowledge, secondary syphilis with coexisting renal a...

To assess the value of serological tests in diagnosing and monitoring the response to treatment of syphilis in patients infected with the human immunodeficiency virus (HIV), case notes of eight homosexual men with a history of treated syphilis, positive reactions to serological tests for syphilis, and documented subsequent conversion to HIV seropositivity were studied. No change was noted in se...

Screening women for syphilis during pregnancy and providing proper treatment are the cornerstones of congenital syphilis prevention. During 2008-2011, 6,221 pregnant women were screened for syphilis using the Rapid Plasma Reagin (RPR) and Treponema Pallidum Hemagglutination (TPHA) tests at R.L. Jalappa Hospital, Kolar, Karnataka, India. The seroprevalence of syphilis during pregnancy ranged fro...

OBJECTIVES Reported cases of congenital syphilis in the Russian Federation increased 26-fold from 1991-9. Our objectives were to describe the frequency, risk factors, and consequences of delivering an infant with congenital syphilis among pregnant women with active syphilis. METHODS In a retrospective record review using consecutive sampling of logs at maternity hospitals in five geographic a...

Syphilis can be spread during the practice of dentistry by direct contact with mucosal lesions of primary and secondary syphilis or blood and saliva from infected patients. The dentist also can play an important role in the control of syphilis by identification of the signs and symptoms of syphilis, patient education, and referral. The incidence of syphilis and the impact of control measures ar...

The manifestations of late syphilis are rarely seen nowadays. In the Oslo study, benign tertiary syphilis occurred in 15-8 per cent. of 1,147 patients with untreated syphilis. The commonest sites of 'benign' tertiary syphilis were the skin, the mucous membranes, and the bones (70 0, 10-3, and 9-6 per cent. of all cases, respectively) (Gjestland, 1955). Thus, syphilis affecting the bones can be ...

OBJECTIVES To evaluate congenital syphilis surveillance in Minnesota, to assess the evaluation and management of newborns at risk for congenital syphilis, and to assess prenatal syphilis screening. DESIGN Case ascertainment and medical record review. SETTING The 7-county Minneapolis-St Paul metropolitan area. PATIENTS Newborns at risk for congenital syphilis during a 3-year period (1992-1...

There appears to be a re-emergence of syphilis in recent times despite a steady decline in incidence for the past decade. Diagnosis of syphilis can be clinically challenging and ocular manifestations of syphilis have a myriad of presentations and severity. Ocular syphilis can occur at any stage of the disease and may also be the only presenting sign of syphilis. We report a case of acute unilat...

OBJECTIVE To determine the diagnostic performance of the SD BIOLINE HIV/syphilis Duo rapid test. DESIGN A hospital-based cross-sectional study. SETTING This evaluation was conducted at one of the largest hospitals in southern Ethiopia. PARTICIPANTS Serum samples obtained from clients attending the antiretroviral therapy and voluntary counselling and testing centres were used. Sera were or...

PURPOSE Between 4-15% of pregnant women are believed to be infected with syphilis in sub-Saharan Africa. Active infection with syphilis in pregnant women results in foetal or infant death or disability for 50-80% of affected pregnancies, and is a major cause of adult morbidity as well. Antenatal syphilis screening is cheap and effective; however, it is often poorly implemented in countries with...