UNLABELLED BACKGROUND Self-reported height and weight are commonly collected at the population level; however, they can be subject to measurement error. The impact of this error on predicted risk, discrimination, and calibration of a model that uses body mass index (BMI) to predict risk of diabetes incidence is not known. The objective of this study is to use simulation to quantify and descr...

X-ray micro-tomography (XMT) is increasingly used for the quantitative analysis of the volumes of features within the 3D images. As with any measurement, there will be error and uncertainty associated with these measurements. In this paper a method for quantifying both the systematic and random components of this error in the measured volume is presented. The systematic error is the offset betw...

Multileaf collimator (MLC) positions should be precisely and independently mea-sured as a function of gantry angle as part of a comprehensive quality assurance (QA) program for volumetric-modulated arc therapy (VMAT). It is also ideal that such a QA program has the ability to relate MLC positional accuracy to patient-specific dosimetry in order to determine the clinical significance of any dete...

A study was performed to determine the relative advantage of computer-controlled couch movement versus manual repositioning to correct patient setup error measured using an electronic portal imaging device (EPID). Twenty-eight on-line setup adjustment trials of anterior-posterior (AP) pelvic projections were evaluated, with 13 setups corrected by automated couch movement determined by direct fe...

Data fusion using Kalman filters requires reasonably good error models. Our intention to fuse line segments, corners and edges obtained from a laser scanner and from advanced sonars provided the motivation on the investigation of Sick PLS laser scanner range measurement reliability, and line segment estimation precision. We present an approach for fitting lines straight in the lasers polar coor...

Knowing the uncertainty of measurements is important for sensor fusion using Kalman filters. Our sensor of interest is the Sick PLS101-112 laser range finder. We present an approach for straight line parameter estimation in polar coordinates that results in a simple covariance estimate and a worst case systematic line parameter error model based on a range error model backed up by experimental ...

The internal validity of an epidemiological study can be affected by random error and systematic error. Random error reflects a problem of precision in assessing a given exposure-disease relationship and can be reduced by increasing the sample size. On the other hand, systematic error or bias reflects a problem of validity of the study and arises because of any error resulting from methods used...

In intensity modulated radiation treatments (IMRT), the position of the field edges and the modulation within the beam are often achieved with a multileaf collimator (MLC). During the MLC calibration process, due to the finite accuracy of leaf position measurements, a systematic error may be introduced to leaf positions. Thereafter leaf positions of the MLC depend on the systematic error introd...