In rodents, oligodendrocytes and myelinating Schwann cells express connexin32 (Cx32) and Cx29, which have different localizations in the two cell types. We show here that, in contrast to Cx32, Cx29 does not form gap junction plaques or functional gap junctions in transfected cells. Furthermore, when expressed together, Cx29 and Cx32 are not colocalized and do not coimmunoprecipitate. To determi...

Myosin IXb, a member of the myosin superfamily, is a molecular motor that possesses a GTPase activating protein (GAP) for Rho. Through the yeast two-hybrid screening using the tail domain of myosin IXb as bait we found BIG1, a guanine nucleotide exchange factor for ADP-ribosylation factor (Arf1), as a potential binding partner for myosin IXb. The interaction between myosin IXb and BIG1 was demo...

Interactive data center applications suffer from the tail latency problem. Since most modern data center applications take the sharded architecture to serve scale-out services, a request comprises multiple sub-requests handled in individual back-end nodes. Depending on the state of each back-end node, a node may issue multiple I/Os for a single sub-request. Since traditional I/O scheduling oper...

The role of economic uncertainty on macroeconomic fluctuations has been studied extensively in the empirical literature; however, its distributional effects have received little attention. This paper attempts to fill this gap by investigating whether affects income, wage, and consumption inequality United Kingdom. Our findings suggest that measures fall significantly a shock. Households middle ...

Amorphous GaN (a-GaN) models are obtained from first-principles simulations. We compare four a-GaN models generated by “melt-and-quench” and the computer alchemy method. We find that most atoms tend to be fourfold, and a chemically ordered continuous random network is the ideal structure for a-GaN albeit with some coordination defects. Where the electronic structure is concerned, the gap is pre...

This note describes an update to the study of linear collider collimation system performance performed by the collimation task force and presented in [1, 2, 3]. In particular, the performance of the NLC collimation system with the addition of “tail-folding” octupoles is described. These octupoles allow the betatron collimation gaps to be opened by more than a factor of three. We present the opt...

Theodorakis, Nicholas G., and Antonio De Maio. Cx32 mRNA in rat liver: effects of inflammation on poly(A) tail distribution and mRNA degradation. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1249–R1257, 1999.—Previous studies showed that the expression of connexin 32 (Cx32), the polypeptide subunit component of the major hepatic gap junction, is reduced in liver by changes i...

The connexins form a family of membrane spanning proteins that assemble into gap junction channels. The biophysical properties of these channels are dependent upon the constituent connexin isoform. To begin identifying the molecular basis for gap junction channel behavior in the human heart, a tissue that expresses connexin43, we used site-directed mutagenesis to generate mutant cDNAs of human ...

The optical absorption coefficient of amorphous 40TeO2-(60-x) V2O5-xMoO3 thin films was determined in a spectral range 190-1100 nm at room temperature. The fundamental optical absorption edge was sharp. The optical gap generally increases as the proportion of MoO3 in the mixed films increases. The width of the tail of the localized states in the band gap was determined for different composition...